Environmental factors associated with nephrotic syndrome include respiratory viruses, EBV, other infections, and allergens. The most common trigger of nephrotic syndrome relapses is upper respiratory tract infections, which precede 50–70% of relapses in SSNS [38,39]. EBV is also a pathogen of in...
Algorithm for the management of children with nephrotic syndrome. Patients are characterized according to response to a 4-week treatment with oral prednisolone (PDN). Patients showing no complete remission enter the confirmation period in which responses to further oral prednisolone (PDN) with or witho...
PedsQLSteroid-sensitive nephrotic syndrome (SSNS)Background: Relapses of nephrotic syndrome are common and are treated with a course of prednisolone (2 mg/kg/day or 60 mg/m(2)/day). This is associated with major adverse effects including diabetes, weight gain, hypertension and behavioural ...