In the vast majority of cases, CNS is a primary glomerular disorder due to genetic defects; occasionally it can however be caused by congenital infections or alloimmune maternal disease [2]. Originally, the disorder has been referred to as the Finnish-type nephrotic syndrome due to its high ...
Nephrotic syndrome is among the most common chronic kidney diseases of childhood. The condition is primary or idiopathic in more than 90% cases. Therapy with prednisone results in complete remission of proteinuria in ~90% patients, termed steroid-sensitive nephrotic syndrome (SSNS). Approximately, 7...
and patients with pediatric nephrotic syndrome present generalized edema. The mechanism of edema includes: (1) reduced intravascular oncotic pressure due to hypoproteinemia; (2) increased resorption of sodium in the epithelial sodium channel (ENaC) in distal renal tubule and collecting tubule and in ...
Many forms of kidney disease in both children and adults may include nephrotic syndrome as part of the picture. To start treating childhood nephrotic syndrome, start with Step 1 below. Part 1 Treating Nephrotic Syndrome 1 Do active home monitoring. This is important and is the opportunity to...
Steroid-resistant nephrotic syndrome (SRNS) is a common cause of chronic kidney disease in childhood and has a significant risk of rapid progression to end