Introduction: Nephrotic syndrome (NS) remains the most common presentation of glomerular diseases in children. Moreover, NS is primarily idiopathic, accounting for 90% of cases, with an average onset age between 2 and 10 years. The objective of our study was to describe the characteristics a...
Proteinuria in glomerular disease is due to increased filtration of macromolecules (such as albumin) across the glomerular capillary wall. The latter consists of three components: the fenestrated endothelial cell, the glomerular basement membrane (GBM), and the epithelial cell foot processes. The pores...
International Study of Kidney Disease in Children, Nephrotic syndrome in children: prediction of histopathology from clinical and laboratory characteristics at time of diagnosis. A report of the International Study of Kidney Disease in Children. Kidney Int. 1978;13(2):159–65. Google Scholar McKinney...
Nephrotic syndrome is the commonest glomerular disease affecting children and is frequently encountered in general paediatrics. The most common subtype is minimal change nephrotic syndrome which typically occurs in preschool children and responds well to corticosteroids. Another subtype, congenital nephrotic ...
. In children, nephrotic syndrome is most commonly caused by minimal change disease ( MCD). Nephrotic syndrome can also be a manifestation of advanced renal disease in systemic conditions (e.g., diabetic nephropathy or amyloid nephropathy). Typical laboratory findings of nephrotic syndrome ...
Nephrotic syndrome is a common kidney disease characterized by heavy loss of protein in the urine, low blood protein levels, high cholesterol levels, and swelling. This disease can occur at any age but is seen more frequently in children compared to adul
Five patients were in the end stage of renal disease within 8 months. Successful maintenance peritoneal dialysis was performed in three patients, but 80% of patients have died of human immunodeficiency virus-related complications; one patient was lost to follow-up. We conclude that immune-complex ...
Idiopathic nephrotic syndrome is a chronic relapsing disease for most steroid-responsive patients, whereas most children with refractory FSGS ultimately develop end-stage renal disease. Research is being done to further elucidate the disorder's molecular pathogenesis, identify new prognostic indicators, and...
Increased risk of idiopathic nephrotic syndrome in children with atopic dermatitis. Pediatr Nephrol 2014;29:2157-63.Wei CC, Tsai JD, Lin CL, Shen TC, Li TC, Chung CJ. Increased risk of idiopathic nephrotic syndrome in children with atopic dermatitis. Pediatr Nephrol 2014;29:2157...
aCause of kidney disease in children 1. Common causes of nephrotic syndrome are caused by many, such as venous thrombosis, cardiac disease, drugs, congenital nephrotic syndrome, hereditary kidney disease, nephrotic syndrome, pregnancy after transplantation of kidney, are in part caused in patients wi...