Cryostat sagittal sections (10 μm thick) from wildtype (WT), claudin-16 knockdown (CLDN16 KD), and claudin-19 knockdown (CLDN19 KD) mouse kidneys were immunolabeled with anti-claudin-16 or anti-claudin-19 antibody to show claudin-16 and claudin-19 localization in the TJs of thick asce...
Xenopus laevis embryos are an established model for studying kidney development. The nephron structure and genetic pathways that regulate nephrogenesis are conserved between Xenopus and humans, allowing for the study of human disease-causing genes. Xenop