Definitions定义Nomenclature命名BiologyofTumorGrowthEpidemiology流行病学MolecularBasisofCancer MolecularBasisofCarcinogenesisAgents(TheUsualSuspects)危险因素HostDefense(TumorImmunity)ClinicalFeaturesofTumors DefnitionofNeoplasia “Aneoplasmisanabnormalmassoftissue,thegrowth ofwhichexceedsandisuncoordinatedwiththatofthenormal...
Intraductal Papillary Mucinous Neoplasm in Patients Under age 50: Tumor Biology, Clinical Features, Recurrence Rates, and Survival OutcomesAcute pancreatitis (AP) is a common presenting symptom of intraductal papillary mucinous neoplasms (IPMN). Our objective was to evaluate the clinical and pathologic ...
Figure 6.Histologic examples of basal cell adenoma vs basal cell adenocarcinoma: (a) A well-circumscribed, cellular neoplasm consisting of basaloid cells without invasion is typical histologic finding of basal cell adenoma. In contrast, basal cell adenocarcinoma shows nests of tumor cells infiltrating ...
Cantril - International Journal of Radiation Oncology*Biology*Physics 被引量: 87发表: 1988年 Abdominoperineal Excision of the Rectum Two patients are presented in whom ischaemic colitis followed some years after abdomino-perineal excision of the rectum for carcinoma. The first patient wa... FSJ ...
Advancing brain tumor therapy: unveiling the potential of PROTACs for targeted protein degradation Saooda Ibrahim Muhammad Umer Khan Qurban Ali Cytotechnology (2025) PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatell...
Here, we deciphered the impact of COX-2, a key modulator of inflammation, in concert with active mutant K-RasG12D on tumor burden and gene expression signature using compound mutant mouse lines. Concomitant activation of COX-2 and K-RasG12D accelerated the progression of pancreatic ...
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is an indolent thyroid tumor characterized by frequent RAS mutations
Immune checkpoint blockers have substantially improved prognosis of melanoma patients, nevertheless, resistance remains a significant problem. Here, intrinsic and extrinsic factors in the tumor microenvironment are discussed, including the expression of alternative immune checkpoints such as lymphocyte activation...
Furthermore, this paper aims to review recent endeavors to elucidate tumor heterogeneity in MPN hematopoietic stem and progenitor cells using single cell technologies. Finally, it will highlight current shortcoming and future applications to advance the field in MPN biology and improve patient ...
In PV, hyperviscosity due to their increased number clearly illustrates their pathogenic potential, but due to the absence of nuclei and nucleic acids, erythrocytes are overlooked in many molecular biology investigations and consequently we lack information about these specialized cells. It is clear ...