Glucose is essential for cerebral metabolism. Unsurprisingly therefore, hypoglycemia may result in encephalopathy. Knowledge of the homeostatic mechanisms
Metabolic encephalopathies (e.g., hypoglycemia) may cause transient EEG abnormalities, yet permanently impair cerebral function. Transient and more benign metabolic abnormalities (e.g., hypocalcemia) cause seizures but are becoming less common with improvements in neonatal intensive care. Meningitis, ...
Siesjo BK, Bengtsson F 1989 Calcium fluxes, calcium antagonists, and calcium- related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J Cereb Blood Flow Metab 9:127– 40 51. Traynelis SF, Cull-Candy SG 1990 Proton inhibition of N-methyl-D-aspartate...
(hypoglycemia [defined as plasma glucose level <2.6 mmol/L {<47 mg/dL} more than 3 hours after birth], treated hyperbilirubinemia, and blood transfusion); (9) in-hospital mortality; (10) length of hospital stay; and (11) breastfeeding at discharge. A composite outcome of respiratory ...
Compared with their full-term counterparts, preterm infants who survive are at higher risk for short-term morbidities including respiratory problems [11], hyperbilirubinemia [12], infections [13], and hypoglycemia [12], as well as long-term adverse neurodevelopmental outcomes including cognitive delays...
with hypoglycemia. No specific diagnosis has been made. T1 weighted (SE 860/20) sequence. Sagittal plane. There are small areas of abnormal high signal intensity within the white matter consistent with acute hemorrhage (arrows). The hemorrhage was seen as low signal intensity on T2 weighted ...
It may have a pathologic basis and can be a fairly prominent sign in neonates with hypoxia, hypoglycemia, hypocalcemia, or drug withdrawal. Jitteriness can be differentiated from seizures by the fact that it can be stopped with gentle restraint and also by an absence of the features commonly ...
[28] found. An adverse effect of insulin therapy was hypoglycemia, which is already in itself a factor of a worse neurological outcome [37]. However, the real risk of hypoglycemia, secondary to insulin, was not well known in preterm infants: Heald et al. [26] did not find a higher ...
Undiagnosed and untreated, hypoglycemia causes brain damage and may lead to death. Early maternal contact and breastfeeding are recommended and highly promoted, including by the WHO, but may be insufficient for preterm and LBW neonates who not only lack energy storage but have limited feeding ...
Hypoglycemia was observed as early as 3 months, while neutropenia and pancreatic insufficiency were observed 11 months later. Genetic testing disclosed the presence of SBDS:c.258+2T>C in trans with the novel SBDS:c.284T>G:p.Val95Arg variant possibly leading to an impaired neutral lipid ...