英[ˈnegətɪv] 美[ˈnɛɡətɪv] 是什么意思 adj. 消极的,否认的;[数]负的;[心]反抗性的;无预期结果的 n. 否定词语;否定的观点;消极性;[摄]底片 vt. 否定;拒绝; 变形 复数:negatives过去式:negatived过去分词:negatived现在分词:negativing第三人称单数:negatives ...
Some antipredation nest boxes can avoid the further enlargement of the nest box entrance, reduce the nest predation rate, and improve nestling survival. Such nest box designs can affect bird population dynamics and produce large-scale changes in life history characteristics (McCleery et al., 1996...
The present meta-analysis is the first to determine common and distinct neuroanatomical markers in anxiety-, fear-related AD and MDD in the context of DSM-5 nosology and psychopathological factor models. GAD exhibited decreased left insula volume relative to HC and FAD, as well as reduced volume...
Sanfilipo MLafargue TArena LRusinek HKushner KLautin ALoneragan CVaid GRotrosen JWolkin A Fine volumetric analysis of the cerebral ventricular system in schizophrenia: further evidence for multifocal, mild-to-moderate enlargement. Schizophr Bull. 2000;26201- 216Google ScholarCrossref 28. Spitzer RL...
Both the CD40-Act1 and BAFF-Act1 knockout mice had much reduced enlargement of lymph nodes and spleen as compared to Act1-deficient mice (data not shown). The hypergammaglobulinemia observed in Act1-deficient mice was abolished in CD40-Act1 and BAFF-Act1 double knockout mice (Figure 3A...
Notably, our preliminary screening found that ANGPTL8 knockout accelerated the development of pathological hypertrophy in vivo and cardiomyocyte enlargement in vitro. This evidence supports the hypothesis that ANGPTL8 may be a negative regulator in pathological cardiac hypertrophy; however, this hypothesis ...
12 Acro mice form pituitary adenomas that mimic human clinical features of acromegaly, including body size enlargement, elevated serum GH and IGF-1 levels, and impaired glucose tolerance and insulin resistance.4,5,6,13,16 Notably, 50-week-old Acro mice exhibited mammary gland tumor development (...
Interestingly, the skeleton of 11-week- old CXXC5 − / − mice, which were visualized by Alizarin red S staining, showed enlargements of the skull, scapula, spine, ribs and limb bones compared with wild-type mice (Figure 1b). For quantitative analysis, BMDs of the 11-week-old mice...
Scale bars, 100 μm. 2.3. Selective suppressive effects of mdn-FGFRs against various FGF ligands As suggested previously, different FGFRs may interact with each other in ligand-mediated complexes (Ueno et al., 1992). The strong effect of mdn-R3 could be due to its ability to heterodimer...
Alzheimer’s disease (AD)-linked β-amyloid (Aβ) accumulates in multivesicular bodies (MVBs) with the onset of AD pathogenesis. Alterations in endosomes are among the earliest changes associated with AD but the mechanism(s) that cause endosome enlargement and the effects of MVB dysfunction on ...