of this noble history, grammarians since the Renaissance have objected to this form of negative reinforcement employing the double negative. In their eagerness to make English conform to formal logic, they conceived and promulgated the notion that two negatives destroy each other and make a positive...
Recently, a renaissance of interest in "negative symptoms," eg, affective flattening or impoverishment of speech and language, has occurred. Although some ... NC Andreasen - 《Archives of General Psychiatry》 被引量: 6134发表: 1982年 Positive and negative symptoms in schizophrenia. A critical rea...
Post-disclosure narratives elaborated (a) the challenges of negotiating post-disclosure relationships with parents, (b) participants' emotional responses to negative parental reactions, (c) participants' efforts to understand and make sense of their parents' reactions, (d) the effects of negative ...
Finally, the development of new antibiotic agents with improved spectrum of activity has the potential to mitigate some of the negative effects of antibiotic resistance although their development is alarmingly slow [48]. There has been a marked reduction since the 1980s in both the number of new...
aSteve Paul Jobs America co-founder, former CEO of Apple Corp.He clung to the Apple Corp decades of ups and downs and Renaissance, has led and launched the Macintosh computer, electronic products, iMac iPod iPhone, iPad and other popular of millions of people worldwide, profoundly changed mod...
PositiveandNegativeImpacts of Postmodernism Having its roots in the Renaissance and the Enlightenment‚ modernism was the era of universal truth which was objectively understood and interpreted by humankind. Postmodernism‚ the period starting around 1950’s to present‚ rejects this notion of an ob...
We further tested the therapeutic effects of mHAdLyp.sT alone and in combination with immune checkpoint inhibitors (ICIs). mHAdLyp.sT alone and with all ICI combinations elicited significant inhibition of lung metastasis by histological analysis. When mHAdLyp.sT was combined with both anti-PD-1 ...
Other associated side effects include acute toxicity such as irreversible cardiotoxicity myelotoxicity, alopecia, nausea, and vomiting [[18], [19], [20]]. Platinum agents have proven to be beneficial for the treatment of TNBC patients when used in combination or as single agents [21]. These ...
Cloud Seeding (CS) has experienced somewhat of a renaissance as the effects of climate change become more severe, and it is seen as a geoengineering solution that could, among other benefits, stymie widespread drought conditions ([113], [114], [115], [116], [117]). In addition, NETs or...
Combined knockdown of CDK4 and CDK6 was able to recapitulate the drug effect at 1 mM but not 5 mM, indicating that the irreversible grown inhibition and high levels of senescence observed at 5 mM could be due to off-target effects at higher palbociclib concentrations (Fig. 1e and ...