Bacterial attachment was studied in ELISA-like assay using a 96-well microtiter plate Maxisorp™ (Thermo Scientific) coated Soya Bean Agglutinin (SBA) lectin (Sigma) in bicarbonate-coating buffer: 5.3 g/L Na2CO3, 4.2 g/L NaHCO3, 1 g/L sodium azide, pH 9.6. Microtiter plate wells were ...
We studied the effects of famotidine, sodium bicarbonate, and citric acid on the 13 C-urea breath test (UBT). Methods. Helicobacter pylori -infected volunteers received a UBT, 40mg of famotidine at bedtime, and a se...
Due to these cell growth-promoting effects and its ability to inhibit apoptosis, TRX has emerged as an attractive molecular target for new anticancer drugs7,8. Thioredoxin-interacting protein (TXNIP), also known as vitamin D3-upregulated an endogenous inhibitor protein-1 or TRX-binding protein-2...
To the best of our knowledge, the effects of different bee venoms and melittin across breast cancer subtypes compared to nontransformed cells have not been investigated. Triple-negative breast cancers (TNBCs, lacking the expression of estrogen and progesterone receptors, as well as human epidermal g...
of vancomycin instillation, studies have looked at the toxic effects of vancomycin when exposed toinvitroskeletal cells via local delivery systems. Antoci et al (2007) concluded concentrations of vancomycin less than or equal to 1mg/ mL had little impact on cell proliferati...
FCV infection causes rapid cytopathic effects, and its replication results in the induction of apoptosis changes in cultured cells. It is well established that the survival of apoptotic cells can be enhanced by the expression of heat-shock proteins (Hsp) to prevent damage or facilitate recovery. ...
Cells were stimulated by 2 μm thapsigargin in the absence of extracellular Ca2+ to passively deplete the intracellular Ca2+ stores followed by restoration of Ca2+ (2 mm) to the extracellular space to assess SOCE. The effects of subsequent addition of either 5 μm Gd3+ or 30 μm 2-APB ...
IFNα/β receptor 1 (IFNAR1) and IFNAR2 form a heterodimeric complex on the surface of cells to recognize secreted type I IFNs and to signal via the classical Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway to induce antiviral effects. More precisely, high-...
of increasing ocean alkalinity, and particularly the impact of harmful trace elements that are present in some alkaline materials7. While the residence time of bicarbonate ions in the ocean is effectively permanent, this may be reduced if alkalinity is elevated7. As such, storage of carbon ...
Those currently under development display a number of side effects that limit their clinical utility, such as liability for abuse and tendency to induce psychosis-like responses. Alternative medications for depression do exist, however many of these suffer from the same need for prolonged treatment ...