6g). The body weight loss can be used as an indicator to evaluate the side effects of the treatment. Negligible differences in the body weights were observed in all treatment groups (P = 0.272, Fig. 6h). Mice rotarod test can be used for evaluation of murine motor coordination and ...
Radiotherapy is increasingly used in the treatment of joint diseases, but limited information is available on the effects of radiation on cartilage. Here, we characterize the molecular mechanisms leading to cellular senescence in irradiated primary cultured articular chondrocytes. Ionizing radiation (IR) ...