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D. (2013). Evaluating the performance of two competing models of school suspension under simulation-the zero-inflated negative binomial and the negative binomial hurdleDesjardins CD. (2013) Evaluating the Performance of Two Competing Models of School Suspension under Simulation– The Zero-Inflated ...
Here, we show that the gut microbe Akkermansia muciniphila can mediate negative effects of IFNg on glucose tolerance. In IFNg-deficient mice, A. muciniphila is significantly increased and restoration of IFNg levels reduces A. muciniphila abundance. We further show that IFNg-knockout mice whose...
Drugs of abuse (e.g., cocaine, opiates) trigger the initial acute-reward effect, lead to adaptive changes in the brain function following administration [1,2,3], and produce unpleasant physical and negative effects, including dysphoria, depression, irritability, and anxiety after the termination o...
iTreg cells within the TME can suppress the anti-tumor effects of CD8+ T cells, natural killer cells, and dendritic cells through multiple mechanisms, thereby promoting tumor progression [14]. We identified Sphingobacterium multivorum (S. multivorum), which showed a high abundance in the tumor ...
To investigate the effects of low-intensity pulsed ultrasound combined with microbubble (LIPUS-MB) mediated JNK/c-Jun pathway reversal on multidrug resistance in triple-negative breast cancer and the underlying mechanisms. An orthogonal experiment was designed to screen for the optimal parameters of LIP...
Incubation of a suspension of C. jejuni 11168H cells with immobilised SBA resulted in bacterial attachment (Figure 1A). This binding was found to be specific as demonstrated by inhibitory effects by both GalNAc and a soluble form of SBA in a dose-dependent manner. The inhibitory effect was ...
Interestingly, the role of IL-13, a key regulator in innate immunity, remains contested in cancer as it may exhibit either pro- or anti-tumorigenic effects depending on context [35]. Compared to all other treatment and control groups, anti-PD-1 therapy dramatically increased serum levels of ...
To determine if the effects ofnctAloss were due solely to the gene replacement and not other mutagenic events from transformation, annctAreconstituted strain was generated. The growth rate of thenctAnull alongside the parent strain MFIG001 (WT) and thenctAreconstituted strain (nctArec) was asses...
3D). Furthermore, the effects of mut-circ-SNRK (no miR-33 binding sites) on ATP synthesis and MMP were similar to pGV486-NC, whereas the effects of circ-SNRK reduction were rescued by miR-33 inhibitor (Fig. 3E/Supplementary Fig. S6D). These results indicated that miR-33 mediates the ...