Although the prognosis of localised prostate cancer is good, the negative effects of prostate cancer treatment often impair patient quality of life. A growing number of men experience these negative effects over a longer time because of the increased inc
In addition to its local effects, the robust radiation of protons, compared to traditional X-rays, is more capable of eliciting the body’s immune response. By activating CD8 + T lymphocytes mediated by dendritic cells, it can achieve immune sensitization effects [5]. The PT approach ...
Objective: The aim of the present study was to investigate the impact of increasing fraction delivery time on the outcome of hypofractionated radiation therapy for prostate cancer.Dasu, AlexandruLinkoping Univ Dept Radiat Phys Linkoping SwedenToma-Dasu, Iuliana...
Adverse effects of radiation therapy (StatPearls Publishing, 2020). Google Scholar Peddie, N. et al. The impact of medication side effects on adherence and persistence to hormone therapy in breast cancer survivors: A qualitative systematic review and thematic synthesis. Breast 58, 147–159 (2021...
Supplementary Fig S2 The effects of PD-L1 and STAT3 on the prognosis of all pathological stage III TNBC patients analyzed by Kaplan-Meier survival curve. a. The effect of PD-L1 on iDFS; b. The effect of PD-L1 on OS; c. The effect of STAT3 on iDFS; d. The effect of STAT3 on OS...
Among breast cancer subtypes, the triple negative breast cancer (TNBC) has the worst prognosis. In absence of any permitted targeted therapy, standard chem
Second, there is a window to design and manufacture the vaccine as the patient recovers from surgery and undergoes adjuvant radiation therapy. Third, there is evidence to suggest that cancer vaccines will be most successful in the adjuvant setting, avoiding the tumor-induced regulatory networks and...
Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer (BC) with a poor prognosis. Current treatment options are limited to surgery, adjuvant chemotherapy and radiotherapy; however, a proportion of patients have missed the su
Prostate cancer at advanced stages including metastatic and castration-resistant cancer remains incurable due to the lack of effective therapies. MiR-190a belongs to the small noncoding RNA family and has an important role in breast cancer metastasis. Ho
(CDK) 4/6 inhibitor ribociclib had synergistic tumor-inhibiting effects on TNBC cells [48]. Although preclinical data of AR inhibitors in combination with CDK4/6 inhibitors have shown promising antitumor effects, relevant clinical trials are still ongoing, and data are not yet available (Table2...