The present results demonstrate the inhibitory effects of gamma-rays and 290 MeV/amu carbon ions on negative gravitaxis of the Euglena gracilis strain Z. The 290 MeV/amu carbon ions had a greater impact at a low dose (<40 Gy) than the 60Co gamma-rays....
In addition to its local effects, the robust radiation of protons, compared to traditional X-rays, is more capable of eliciting the body’s immune response. By activating CD8 + T lymphocytes mediated by dendritic cells, it can achieve immune sensitization effects [5]. The PT approach ...
In view of the discovery that hard gamma-rays of Th C′′ give rise to positives and negatives in pairs, similar to the effects found in cosmic-ray studies, it is concluded that the absorption of the Th C′′ rays is due in part to that by free negative electrons and in part to a...
tuber- culosis and effects the presentation of adhesion molecules [38]. IL-17A has been found to be a significant cytokine in the immune reaction against mycobacterial infection [39]. Investigations have showed that the IL-17A-producing γδ T cells were main source of IL-17A [40]. Our ...
In this study, we investigated the effects of MK-8776 on the radiosensitivity of 3 human triple- negative breast cancer (TNBC) cell lines MDA-MB-231, BT-549 and CAL-51. MK-8776 dose-dependently inhibited the proliferation of MDA-MB-231, BT-549 and CAL-51 cells with IC50 values of ...
I to LC3-II in the cells. Pretreatment with the low dose of MK-8776 suppressed these effects. The above results suggest that MK-8776 increases human TNBC radiosensitivity by inhibiting irradiation-induced autophagy and that MK-8776 may be a potential agent in the radiosensitization of human TNBC...
The present invention relates to methods of treating immune disorders and cancers. In particular the invention provides methods of inhibiting the negative immunomodulatory effects of ERp-5 on T cells and dendritic cells, in conjunction with other surface receptors.Inventors...
Profound immunomodulatory effects of 225Ac-NM600 drive enhanced anti-tumor response in prostate cancer An immunosuppressive tumor microenvironment has hampered the efficacy of immunotherapy in prostate cancer. However, radiation-induced immunological effects... C Ferreira,HK Potluri,CF Massey,... - 《...
incidence of tumours/ A8750G Biological effects of ionizing radiations (UV, X-ray, gamma-rayparticle radiation effects)Long-term effects, especially the incidence of tumors, of whole-body exposure of female NMRI mice with either negative pions (peak or plateau region) or X rays have been ...
There was also an increase in granularity due to a high grain yield where several grains were rendered developable by the same gamma (y)-ray photon. The effects of silver coating weight and emulsion grain size on the granularity induced by ionizing radiation were also studied. II was concluded...