14Citations 84Altmetric Metrics Abstract The high stiffness of intravenous needles can cause tissue injury and increase the risk of transmission of blood-borne pathogens through accidental needlesticks. Here we describe the development and performance of an intravenous needle whose stiffness and shape dep...
Parenteral administration routes maintain predominance in vaccination protocols, offering superior bioavailability through gastrointestinal bypass. Primary methodologies include intramuscular, subcutaneous, and intradermal injections. The integumentary system functions simultaneously as a protective barrier and immunological...
This has required the development of protocols to sort viable CTC starting from large blood volumes (being CTC extremely rare), as well as the optimization of long-term culture protocols and of patient-derived xenografts [65]. In 2013, Marchetti's group established long-term primary cultures of...