It most often affects people between the ages of 30 and 60, meaning it can cause serious long-term effects. An X-ray indicating avascular necrosis in the knee. Lesson Quiz Course 2.3K views Causes of Avascular Necrosis We don't always think of bone as a living tissue, but it i...
The database also contains medical information on the presence of any serious and costly long-term disease giving entitlement to 100% health insurance coverage based on the French National Health Insurance list of 30 eligible chronic conditions,15 with information on diagnosis encoded in the ...
Three repurposed drugs initially developed for other conditions32,42,43have shown particular promise as potential drug therapies for snakebite envenoming based on in vitro and rodent in vivo data: the SVMP-inhibiting metal chelator, DMPS (Unithiol)32, the hydroxamic acid, marimastat33,34,36,44...
An increasing number of patients are adult long-term survivors that may suffer the sequelae of radiation therapy during childhood, particularly radiation-induced bone growth arrest and osteonecrosis with complex nonunions. The orthoplastic approach, meaning the combination of skeletal and soft-tissue ...
The term "immunogenicity" as used herein refers to a measure of the ability of a protein 30 or therapeutic moiety to elicit an immune response (humoral or cellular) when administered to a recipient. Preferably the chimeric fusion polypeptides of the present WO 2013/124666 PCT/GB2013/050433 35...
Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis. The study is among the first to acknowledge that even short-term use of common oral osteoporosis drugs may leave the jaw vulnerable to...
Myocarditis was not only identified as the cause of death in multiple COVID-19 patients [19] but also as a concerning type of COVID-19-induced long-term cardiovascular complication [20]. Although myocarditis remains a relatively rare condition, one study found a 16-fold increased risk of myoc...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), utilizes the host receptor angiotensin-converting enzyme 2 (ACE2) and the auxiliary receptor Neuropilin-1 (NRP1) to enter host cells. NRP1 has another isoform, NRP2, whose function...
1, Ravindran Thayan 1, Dayang Fredalina Basri 3and Wei Boon Yap 2,* 1 Virology Unit, Infectious Disease Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Bandar Setia Alam, Shah Alam 40170, Malaysia ...