Recently, tumour necrosis factor-related activation-induced cytokine (TRANCE) was shown to be necessary for osteoclast formation. We now report that TGF(be... K Fuller - 《Journal of Cell Science》 被引量: 792发表: 2000年 Activation of the bone-derived latent TGF beta complex by isolated ost...
The process of bone remodeling is primarily carried out by two types of cells, osteoblasts and osteoclasts. Osteoblasts synthesize the protein matrix that mineralizes to become bone; whereas osteoclasts demineralize and resorb bone. The intricate balance between their activities is critical for bone ...
Zhao,M,Harris,SE,Horn,D,Geng,Z,Nishimura,R,Mundy,GR.Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation. The Journal of Cell Biology . 2002Zhao M, Harris SE, Horn D, et al. Bone morphogenetic protein receptor signaling is necessary for normal ...
How many cell types of MSC can converted into and what function of these cell types in tumour progression? 3. Whether MSC exosomes can be a meaningful tool for future therapy? Introduction In the 1960s, a subtype of fibroblasts originating from bone marrow that possessed colony forming capacity...
Longitudinal bone growth, achieved through endochondral ossification, is accomplished by a cartilaginous structure, the physis or growth plate, comprised of morphologically distinct zones related to chondrocyte function: resting, proliferating and hypert
and controls nausea in some women. Calcium helps bone development of the child and prevents high blood pressure as well as leg cramps in pregnant women. Vitamin C is important for formation of collagen which is a part of connective tissue, cartilage and bone. 年份: 2007 ...
Both cell types are involved in the production and accumulation of hemoglobin (Hb) that is necessary to proerythroblast formation. This process is known as the proliferation stage [6], [7]. For Hb biosynthesis, cells take up iron from two major sources. One pathway for iron acquisition is ...
Cylindromatosis protein (CYLD) is a tumor suppressor that displays a specific ubiquitin hydrolase activity for K63-linked polyubiquitin chains (13). Negative regulatory actions of CYLD have been reported for several signaling paradigms, the most explored to date being its role in the NF-kB pathwa...
Autophagy is a well-known cellular process involved in many physiological and pathological processes. During erythropoiesis, autophagy plays an important role participating in the clearance of unnecessary organelles such as ribosomes and mitochondria (mitophagy) allowing the correct formation of mature red ...
What condition describes bone formation in nonosseous tissues and is most common after a fracture or surgical procedure? Heterotopic Ossificatioin What are some common muscles you should strengthen with stress incontinence? 1. Adductors 2. The pubococcygeus (part of the pelvic diaphragm) ...