32 Both FEnS and AEnS responded to the HS challenge based on the transcriptional activation of proinflammatory cytokines TNF and CXCL8/IL8 (Figure 7A and B). However, response from younger FEnS (F11, F15, and F17.5) was modest and not significant, whereas more mature F21.5 and F22.5 ...
M1 polarization and promoted M2 polarization via STAT3 activation. Addition of HB- EGF to LPS-stimulated macrophages suppressed the pro-apoptotic effects of the macrophages on FHs-74 cells. In vivo, we found enhanced intestinal macrophage infiltration in pups subjected to NEC, the majority of which...
HIF-2alpha regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma. J Cell Mol Med. 2017;21(11):2896–908. 63. Kong L, Liu P, Zheng M, Xue B, Liang K, Tan X. Multi-omics analysis based on integrated genomics, ...