This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53...
编码蛋白是p53介导的caspase活化和凋亡的必要条件该基因突变是4d型腓骨肌萎缩症的病因之一,该基因的表达可能是多种癌症的预后指标。另外,已经观察到该基因编码多个亚型的剪接转录变体[由RefSeq提供,2012年5月] This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrol...
Gene Name: VIM Protein Name: nan Human Gene Id: 7431 Swiss-Prot: P08670 Formulation: nan Source: nan Dilution: nan Purification: nan Concentration: nan Storage&Stability: 4°C/6 months Background: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially ...
NDRG1 导读 基因简介 中英文全称:N-myc 下游调控基因1 N-myc downstream regulated gene 1 分布:核 活性:催化 参与:应答金属离子|细胞分化 病变:Charcot-Marie-Tooth 病(进行性神经性腓骨肌萎缩), 4D OMIM/位置:605262 8q24.3
摘要:细胞生长、分化和多种应激的情况都可以影响NDRGI(N-myc downstream-rvgulatcd gene 1)蛋白的表达水平。NDRG1在许多细胞的正常生理功能中起着重要作用。NDRG1的缺乏可能导致多种疾病,如.碡D型CMTD(夏-马-图三氏病进行性神经性肌萎缩,Charcot-Marie-Toothdisease)的发生与施万细胞中NDRG1的缺失有关。在多...
the sensitivity of CTX in patients with right hemi-colon cancer is much lower than that in patients with left hemi-colon cancer. This significantly limits its clinical application. Therefore, further elucidation of the under...
货号 SB-KO15216 英 文名 NDRG1 gene knockout A549 cell pool (non monoclonal) 规格 1T 品牌 圣尔生物share-bio 021-34122580 加入收藏夹 产品编号 名称 包装 品牌 目录价 促销价 货期 数量 购物车 SB-KO15216 NDRG1基因敲除A549细胞pool(非单克隆) 基因水平验证KO效率>70%(如需WB验证加3000元及...
N-myc下游调节基因( N-myc downstream regulated gene , NDRG)1属于NDRG家族,α/β水解酶超家族,但没有水解酶催化位点[1].最初是在N-myc敲除的小鼠胚胎组织中发现的,受 N-myc 的抑制而得名. NDRG1位于人类染色体8q24,全长约60 kb,包括16个外显子和15个内含子,含有一个与第1外显子和第1内含子5′...
重组人N-myc下游调节基因蛋白1(NDRG1) 英文名称:Recombinant Human N-myc Downstream Regulated Gene 1产品规格:10μg|50μg|500μg|1mg发货周期:1～3天产品价格:询价本产品仅可用于科研实验,严禁用于其他非科研用途!本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Cys394在N端含有His标签。