近日,上海交通大学医学院附属仁济医院检验科李敏教授团队在国际高水平期刊《Drug Resistance Updates》(中科院1区,2023年影响因子15.8)上在线发表了题为《Emergence of Silent NDM-1 Carbapenemase Gene in Carbapenem-SusceptibleKlebsiella pneumoniae: ...
近日,上海交通大学医学院附属仁济医院检验科李敏团队在在临床耐药菌研究领域权威期刊《Drug Resistance Updates》(《药物耐药进展》,中科院1区)上在线发表了题为《Emergence of Silent NDM-1 Carbapenemase Gene in Carbapenem-Susceptible Kleb...
In addition, since the blaNDM-1 gene that produces the enzyme is often associated with other genes that code for other antibiotic-resistance factors, they are concerned that such resistance will be quickly passed to most gram-negative bacteria, thus rendering a huge group of bacteria resistant to...
新德里金属β-内酰胺酶-1碳青霉烯类敏感性克隆Objective To determine new delhi metallo-β-lactamase-1 (NDM-1 )gene in strains of gram-negative bacilli with de-creased sensitivity to carbapenems,and to investigate the epidemic situation of strains carrying NDM-1 gene in Guangzhou area. Methods 105...
DM 基因亚型,全称 New Delhi metallo-beta-lactate dehydrogenase gene,是一种β-内酰胺酶基因,编码产生碳青霉烯酶,可以使得细菌对大多数抗生素产生抗药性。该基因亚型首次于 2009 年在印度新德里发现,随后在全球范围内迅速传播,引起了医学界的广泛关注。 DM 基因亚型可以分为两大类,分别是 NDM-1 和 NDM-2。其中...
近日,上海交通大学医学院附属仁济医院检验科李敏团队在在临床耐药菌研究领域权威期刊《Drug Resistance Updates》(《药物耐药进展》)上在线发表了题为《Emergence of Silent NDM-1 Carbapenemase Gene in Carbapenem-Susceptible Klebsiella pneumoniae: Clinical Implications and Epidemiological Insights》的最新研究成果,文章揭示...
Pets with NDM-1 could be a dangerous vector of infection, since people have close contact with them. The finding was announced M2M gateway by Rajesh Nayak, a research scientist at the FDA’s National Center for Toxicological Research in Jefferson, Arkansas. The gene, blaNDM, was found in iso...
PCRmethodwasdevelopedtodetectNDM-1gene.Specificprimersweredesignedbasedonthegenese-quenceinGeneBank.TheprimersusedinthisassaywereshowntobespecificforplasmidwithNDM-1anddidnotreactwithother11standardbacteriastrains.Thistechniquewassensitivewiththedetectionlimitof ...
他们的研究成果,题为《Emergence of Silent NDM-1 Carbapenemase Gene in Carbapenem-Susceptible Klebsiella pneumoniae: Clinical Implications and Epidemiological Insights》,近日在国际权威期刊《Drug Resistance Updates》上发表。该研究揭示了在对抗菌药物敏感的肺炎克雷伯菌中,存在沉默型NDM-1耐药基因(blaNDM-1),这...