NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice.IFN‐γInnate lymphoid cellsMucosal immunologySTAT4TranscriptomeInterleukin-6 (IL-6) and IL-27 signal through a shared receptor subunit and employ the same downstream STAT transcription...
可促进NCR+ILC3分化及相关细胞因子分泌,抑制LTi ILC3分化,调节LTi ILC3/NCR+ILC3细胞免疫平衡,进一步印证了NCR+ILC3受丁酸诱导,与共生微生物互为调控,保护肠道黏膜屏障的机制.结论五味苦参肠溶胶囊治疗DHAS-UC具有充分的临床依据,该药通过直接作用于肠道黏膜层及菌群,上调代谢产物丁酸含量,从而促进NCR+ILC3的分化...
Dendritic Cells Promote the Differentiation of ILCs into NCR−ILC3s in the Lungs of Mice Exposed to Cigarette Smoke Showing 1/2:icop_a_2389909_sm0479.pdf 92views 0shares 30downloads Sorry we could not load your data. Data availability statement ...
Dendritic Cells Promote the Differentiation of ILCs into NCR−ILC3s in the Lungs of Mice Exposed to Cigarette Smoke Caixia Liang, Ying Shen, Yifang Xu, Yi Liang, Shilin Qiu, Haijuan Tang & show all Article: 2389909 | Received 19 Feb 2024, Accepted 02 Aug 2024, Published online...
Results NCR þ ILC3 accumulate in NSCLC tissues. We have previously shown that a CD3negCD56 þ NKp44 þ cell population selectively infiltrates NSCLC, whereas it is virtually undetectable in normal lung tissues42. In addition, NCR þ cells are mainly localized in the tumour stroma, in ...
Product Datasheets Product Datasheet COA SDS Related Research Areas Group 1 ILCs ITIM/ITAM Immunoreceptors and Related Molecules Natural Cytotoxicity Receptors (NCRs) and Ligands Natural Killer T (NKT) Cells NCR+ILC3 NCR-ILC3
Product Datasheets Product Datasheet COA SDS Related Research Areas Group 1 ILCs ITIM/ITAM Immunoreceptors and Related Molecules Natural Cytotoxicity Receptors (NCRs) and Ligands Natural Killer T (NKT) Cells NCR+ILC3 NCR-ILC3 Related Products All Products for NKp44/NCR2 NKp44/NCR2 Pri...
Runx3 fl/fl PLZF-cre mice were much more sensitive to infection with the intracellular bacterial pathogens S. typhimurium and L. monocytogenes partially due to abnormal Group 1 ILC and NCR + ILC3 function. We also found that Runx3 directly binds to the Il12R β 2 promoter and intron 8 ...
下图为临床前研究中常用的三种小鼠品系(C57BL/6NCr、BALB/cAnNCr和129/SvHsd)中关键免疫细胞类型,根据品系和性别统计的均数分布。 a图显示的是 C57BL/6NCr、BALB/cAnNCr 和 129/SvHsd 小鼠骨髓中 CD4+ 和 CD8+ T 细胞、Treg...
(ILC) 1, and a small population of T lymphocytes (1). NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCRs) (2). The NKp46 and NKp30 receptors play a major role in triggering some of the key lytic ...