美国国家癌症网络(NCCN)的肿瘤治疗指南是全世界最权威的治疗指南之一,目前 NCCN 前列腺癌指南已更新至 2023 V1 版[1],相较 2022 V4 版[2]本文整理了新版指南更新中的 4 个要点: 1.初始根治性治疗后的直肠指诊,强调怀疑复发即可进行; 2.将「未经去势治疗...
结语 此外,2023 V1版前列腺癌NCCN在风险分层原则、影像学原则、主动监测和观察原则、放疗原则、手术原则、雄激素剥夺治疗原则和非激素系统治疗原则均有更新,详见指南原文,也可留言告诉小编您感兴趣的内容,以便我们后续整理编译。 参考文献: NCCN Clinica...
2023年5月,FDA批准奥拉帕利联合阿比特龙治疗BRCA突变mCRPC成人患者。根据PROpel试验的结果,奥拉帕利/阿比特龙被纳入NCCN指南,作为有致病性BRCA1或BRCA2突变(胚系和/或体细胞),且尚未接受新型激素疗法或多西他赛治疗的mCRPC患者(1类),以及既往在去势敏感情况下接受过多西他赛治疗的mCRPC患者(2A类)的一线可选方案。 ▲2023年...
戈舍瑞林微球已于2023年6月作为2.2类新药获批上市,成为前列腺癌患者去势治疗的重要选择之一。 参考文献 参考文献: [1] Prostate cancer-NCCN Guidelines Version 4.2023. [2] Prostate Cancer-NCCN Guidelines Version 4.2022. [3] Prostate Cancer-NCCN Guidelines Version 2.2023. [4] de Bono JS, Mehra N, Scagl...
Cancer NCCNProstateCancerDmsunnion Network SYSTEMICTHERAPYFORCASTRATION-SENSITIVEPROSTATECANCER Monitortingtpreferred)| Mo*s,or ADruuu|See |Studies Systemis |Physicalexam+nogatlve Therapyfot PSAovery3-6mofordistant MOCRPC ADTwithoneofthefollowing:motstase ...
新版NCCN指南将未经去势治疗前列腺癌(castration-naive prostate cancer)调整为去势敏感性前列腺癌(castration-sensitive prostate cancer,CSPC),更加精准地定义治疗人群。 同时,基于ARASENS和PEACE-1研究,CSPC的系统治疗不再推荐以多西他赛为基础联合ADT的二联方案,修改为在多西他赛耐受患者中推荐ADT+多西他赛基础上联合新型内...
Prostate cancer dis-proportionately affects mortality in Black patients compared to White patients at a 2.1-fold higher death rate. However, this racial disparity is not accounted for when including patients in research.METHODS The studies referenced in the latest NCCN guidelines were evaluated for ...
“Although androgen-deprivation therapy is still the backbone of therapy for metastatic hormone-sensitive prostate cancer, the treatment landscape has progressed to include doublet and triplet therapies.” —Archana Ajmera, MSN, ANP-BC, AOCNP ...
参考文献: [1] NCCN Clinical Practice Guidelines in Oncology:Bladder Cancer(Version 3.2022) [2] NCCN Clinical Practice Guidelines in Oncology:Kidney Cancer (Version 4.2023) [3] NCCN Clinical Practice Guidelines in Oncology:Prostate Cancer Early Detection(Version 1.2023)©...
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