211. Walsh T, Casadei S, Coats KH, et al.Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high riskof breast cancer. JAMA 2006;295:1379-1388. 212. Walsh T, Lee MK, Casadei S, et al.Detection of inherited mutations for breast and ovarian cancer using genomicc...
9.Tung N, Battelli C, Allen B, et al. Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel. Cancer 2015;121:25-33. 10.Castéra L, Krieger S, Rousselin A, et al. Next-generation sequencing f...
该研究由Shankar Balasubramanian教授领导进行,相关成果已于8月3日发表在Nature Genetics上,文章题为“Landscape of G-quadruplex DNA structural regions in breast cancer”。 03 【Future Oncology】:阿法替尼序贯奥希替尼用药将EGFR突变阳性NSCLC患者OS延长至近4年勃林格殷格翰公司(Boehringer Ingelheim)近日宣布了一项...
70.8% of referred patients, consulted with genetics. Among those who consulted with genetics, 95.2% underwent testing. Conclusions Although increasing, genetic counseling remains underutilized across cancer diagnosis. Women with breast cancer are more likely to be referred than women with gynecologic ...
Adherence Patterns to National Comprehensive Cancer Network Guidelines for Referral of Women With Breast Cancer to Genetics Professionals. Genetic predisposition is responsible for 5% to 10% of breast cancer. The National Comprehensive Cancer Network (NCCN) established guidelines delineating a... Ashley,St...
Genetics, genomics, and cancer risk assessment:Stateof theartand future directions in the era of personalized medicine. CA Cancer J Clin 2011;61:327-359. 6.Schneider K, DiGianniL, PatenaudeA, et al.Accuracy of cancer family histories: comparison of two breast cancer syndromes. Genet Test ...
Breast Cancer Update Kilian E. Salerno, MD “We hope to move away from the concept of standard fractionation being ‘conventional,’ because I would argue that for breast radiotherapy, hypofractionation is standard as well.” —Kilian E. Salerno, MD ...
BreastCancerRiskReduction PracticeGuidelines inOncology–v.2.2010NCCN ® GuidelinesIndex BreastRiskReductionTOC Discussion,References NCCNBreastCancerRiskReductionPanelMembers ThereseB.Bevers,MD/Chair TheUniversityofTexasM.D.Anderson CancerCenter DeborahK.Armstrong,MD TheSidneyKimmelComprehensiveCancer CenteratJohns...
cancer sarcoma adrenocortical carcinoma brain tumors endometrial cancer leukemia lymphoma thyroid cancer dermatologic manifestations and or macrocephaly diffuse gastric cancer Also for an unaffected individual A known mutation in a breast cancer susceptibility gene within the family was moved as the first ...
“NCCN”, the NCCN logo, and “National Comprehensive Cancer Network” are registered trademarks of the National Comprehensive Cancer Network. The Chinese edition of NCCN Clinical Practice Guidelines in Oncology-Breast Cancer Guideline 2010 is the Chinese adapted version of NCCN Clinical Practice ...