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单克隆抗体NCC-ST-439用于癌症诊断 下载积分: 2990 内容提示: 卫 述鱼崖 血卿丝旦经鱼1 叁签 生夕1 7 3单 克隆杭体N C C 一 S T一4 3 9用 于癌症诊 断单克 隆 抗体 N C C一S T一呼 3 9是·用人胃癌细胞株S卜 , 作免 疫原制成 的单 克隆 抗体,在多 种癌组织中 发现 率较高。为了...
NCC-ST-439为一种单克隆抗体,用它作新的肿瘤标记正引起人们的重视.高桥等对已被病理确诊为原发性女性乳癌81例为对象测定其血清中NCC-ST-439值.其临界值采用该协会的标准,49岁以下为7.0μ/ml,50岁以上为4.5μ/ml.测定值大于cut off值者为阳性.测定结果是,原发性乳癌的NCC-ST-439平均值为41.51±221.45μ/...
应用McAb免疫组化法对癌细胞和正常细胞抗原的局部表现进行了研究.NCC-ST-439抗原阳性为细胞检出率:子宫颈癌31/45例(68.9%),子宫体癌13/20例(65.0%),子宫平滑肌肉瘤0/2... 郑建华,孙云桥,王纯香,... - 《哈尔滨医科大学学报》 被引量: 0发表: 1992年 [Gastrointestinal cancer] CA 72-4 and NCC-ST-4...
【摘要】@@ SLX是检出由癌细胞产生的糖链的一种肿瘤标志物,检测此标志物糖链称为唾液酸化Lex-i 或唾液酸化SSEA-1.检出类似糖链的肿瘤标志物还有NCC-ST-439、CSLEX(唾液酸化Lex抗原).他们均与唾液酸结合,加上不同程度的岩藻糖,以检出附加Lex系统的二型基干糖链. 【总页数】3页(P60-62) 【作者】神奈木...
NCC-ST-439 is a glycoprotein recognized by a monoclonal antibody (ST-439) which is obtained by using a human gastric cancer xenograph, ST-4, as an immunogen. Using a Lana Enzyme Kit from Nippon Kayaku, we measured the serum level of NCC-ST-439 in 223 patients with lung cancer, 344 ...
Eval- uation of cancer-associated carbohydrate antigen NCC-ST-439 meas- urement in pure pancreatic juice collected by endoscopic aspiration. Dig. Endosc., 2: 141-147, 1990.Takemori Y, Sawabu N, Ohta H, Satomura Y, Watanabe H, Yamakawa O, et al. Evaluation of Cancer-Associated ...
The results of a preliminary study suggested NCC-ST-439doi:10.1007/BF02482979KoichiMatsumotoTsunekiKinoshitaTomomiIshidaHidekiItohChikaoMikiHiroshiSurg TodaySurgery TodayMatsumoto K, Kinoshita T, Ishida T, Itoh H, Miki C, Suzuki H: Serum levels of NCC-ST-439 in Dukes' C colorectal cancer patients...
NCC-ST-439Tumor markerLung cancerAfter we performed immunostaining for NCC-ST-439 using ST-439, positive immunoactivity was demonstrated mainly in the membrane of adenocarcinoma cells. NCC-ST-439 thus seems to be a tumor associated marker in patients with lung adenocarcinoma....
识别用作肿瘤标记物的糖链抗原的抗体的抗原特异性不充分,因而在使用了这样的抗体检测肿瘤标记物时,存在检测特异性降低,癌症诊断的准确性降低的问题.为了解决上述课题,本发明提供与用作肿瘤标记物的NCCST439抗原的糖链进行特异性反应的抗体及其制造方法.三浦知启宫崎修...