雄激素处理和AR过表达增加了PCa细胞系中NCAPD3的表达。经典存在于NCAPD3的增强子区。雄激素/AR轴在细胞有丝分裂过程中调节NCAPD3相关的染色体凝聚。 结论:我们的报告表明,NCAPD3是一种雄激素反应性基因,受雄激素/AR轴上调,并参与AR促进的前列腺癌进展,这表明NCAPD3在前列腺癌发展中的潜在作用。 其中体内RNA转...
抗体名:NCAPD3 亚型:详情见说明书 浓度:95 % 是否单克隆:否 靶点:详情见说明书 免疫原:详情见说明书 宿主:Rabbit 用途:仅供科研 保质期:一年 应用范围:ELISA, WB, IHC, ICC/IF 产地:武汉 标记物:详情见说明书 品牌:艾普蒂生物 包装规格:10ul ...
Immunogen NCAPD3 fusion protein Ag10429 种属同源性预测 Host / Isotype Rabbit / IgG Class Polyclonal Type Antibody Full Name non-SMC condensin II complex, subunit D3 Synonyms CAP D3, CAPD3, CNDD3, Condensin 2 complex subunit D3, hCAP D3, hCAP-D3, hcp 6, hHCP 6, KIAA0056, NC...
抗体检测数据 (1) Application 图: 1 / 1 NCAPD3 Antibody (PA5-65262) in ICC/IF Immunofluorescent staining of NCAPD3 in human cell line HEK 293 shows localization to nucleoplasm. Samples were probed using a NCAPD3 Polyclonal Antibody (Product # PA5-65262). View more ...
PrEST Antigen NCAPD3 供应商 Atlas Antibodies 产品货号 APrEST90903 产品报价 ￥询价/100ul 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。 产品新闻 背景资料 Atlas Antibodies品牌可称为精品抗体供应商,武汉艾美捷科技作为Atlas Antibodies品牌...
NCAPD3 overexpression also accelerated tumor growth in the xenograft mouse model and repressed miR-30-5p. In summary, this work elucidates NCAPD3 inhibits miR-30a-5p through two pathways: increasing STAT3-MALAT1 to sponge miR-30a-5p and increasing MYC to directly ...
NCAPD3激活AKT-FOXO信号通路抑制前列腺癌细胞的凋亡
NCAPD3 is one of the three non-SMC subunits of condensin II complex, which plays an important role in the chromosome condensation and segregation during mitosis. Notably, elevated levels of NCAPD3 are found in many somatic cancers. However, the clinical
NCAPD3 exerts tumor-promoting effects in prostatic cancer via dual impact on miR-30a-5p by STAT3-MALAT1 and MYC Non-SMC condensin II complex subunit D3 (NCAPD3) is a subunit of the non-structural maintenance of chromosomes condensin II complex, which involves chromos... Y Zhang,Y ...
NCAPD3,CXCL13组肿瘤明显大于对照组,而过表达AR-N再抑制NCAPD3和CXCL13组肿瘤明显小于过表达AR-N组,在对照组中敲低NCAPD3后形成肿瘤小于对照组,但各组小鼠的体重没有明显变化;Western blot和免疫组织化学结果显示过表达AR-N,NCAPD3均能提高ETS-1,Cyclin D1和Snail的表达,而敲低NCAPD3后显著削弱AR的调节...