【年(卷),期】2014(034)004 【总页数】4页(P10-12,45) 【关键词】福尔马林炎性疼痛;电压门控钠离子通道1.7;背根神经节;大鼠 【作者】王波;邵先舫;刘志军;陈绍军;李前;贺渊哲;钟佳 【作者单位】湖南中医药大学研究生院,湖南长沙410007;湖南中医药大学附属常德医院,湖南常德415000;湖南中医药大学附属常德医院,...
公开 公开 2014-08-13 实质审查的生效 实质审查的生效 2017-06-06 发明专利申请公布后的视为撤回 发明专利申请公布后的视为撤回 权利要求说明书 Nav1.3和Nav1.7的强效及选择性抑制剂的权利要求说明书内容是...请下载后查看 说明书 Nav1.3和Nav1.7的强效及选择性抑制剂的说明书内容是...请下载后查看©2022...
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。 成立日期2014-05-08(11年)注册资本100万元整 员工人数10-50人年营业额￥ 100万以内 ...
57, 6623–6631 (2014). 29. Henriques, S. T. et al. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes is a Prerequisite for its Inhibition of Human Voltage-gated Sodium Channel NaV1.7. J Biol Chem 291, 17049–65 (2016). 30. Smith, J. J., Cummins, T. R., ...
截图自药融云数据库Xenon创立于1996年,2014年登陆纳斯达克(NASDAQ:XENE),截至2024年3月22日,该公司市值超过33.19亿美元,是加拿大少有的市值较高的创新药企。Xenon的过去:“世界首个”基因疗法与疼痛研究Xenon创立之时正值基因组技术取得长足发展的时期,最初公司名为Xenon Bioresearch,2004年更名为Xenon Pharmaceuticals。
Cite this article Crystal structure of the prokaryotic NavM sodium channel to model human Nav1.1 (SCN1A).Science-Business eXchange7, 748 (2014). https://doi.org/10.1038/scibx.2014.748 Download citation Issue Date26 June 2014 DOIhttps://doi.org/10.1038/scibx.2014.748...
57, 6623–6631 (2014). 29. Henriques, S. T. et al. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes is a Prerequisite for its Inhibition of Human Voltage-gated Sodium Channel NaV1.7. J Biol Chem 291, 17049–65 (2016). 30. Smith, J. J., Cummins, T. R., ...
A crystal structure of CaM and FGF13U bound to the NaV1.2 CTD (4JPZ) showed CaMN positioned near post-IQ residues (Wang et al., 2014), whereas crystal structures of CaM bound to CTD fragments of NaV1.4 and NaV1.5 showed CaMN near the EFL (Yoder et al., 2019). To determine ...
Lamouille, S., Xu, J., & Derynck, R. (2014). Molecular mechanisms of epithelial-mesenchymal transition.Nature reviews. Molecular cell biology15 ArticleCASPubMedPubMed CentralGoogle Scholar Huang, R. Y., Guilford, P., & Thiery, J. P. (2012). Early events in cell adhesion and polarity...
Overfitting of the overall model was monitored by refining the model in one of the two independent maps from the gold-standard refinement approach and testing the refined model against the other map (Amunts et al., 2014). Statistics of the 3D reconstruction and model refinement is summarized ...