The 2024 Nobel Prize in Chemistry has been awarded to David Baker “for computational protein design” and to Demis Hassabis and John M. Jumper “for protein structure prediction”. In recognition of this award, Nature Portfolio presents a collection of research, review and opinion articles that ...
Structure of the yeast ceramide synthase Using cryo-electron microscopy, Schäfer et al. solved the structure of the yeast ceramide synthase complex, consisting of Lip1, Lag1 and Lac1 subunits. They found that fumonisin B1 binds competitively at a key site, suggesting a mechanism for ceramide...
Structure, Nature Meet in Digital PhotosFor the past three years, many who have made their way to PanzaGallery and Frame in Millvale...By ShawKurt
近日,物理学系田传山课题组在电化学界面的原位表征上取得进展。相关成果以“Structure evolution at the gate-tunable suspended graphene-water interface”为题,于2023年8月30日发表在Nature杂志上。 作为主要的电催化剂载体和层状插层基质,石墨电极在能量转换和存储领域有着广泛应用。与石墨相似,石墨烯作为石墨的二维结...
这使人们得以一窥粗丝内部的分子分布和成分排列。这一新发现是理解肌肉在健康和疾病状态下如何运作的重要框架。相关研究结果于2023年11月1日在线发表在Nature期刊上,论文标题为“Structure of the native myosin filament in the relaxed c...
与教学任务相比,研究工作对研究生心理健康问题的影响更大。在研究过程中,工作缺乏清晰结构或方向(lack of structure)也会使学生感到迷茫和压力,加重焦虑症状。 比如,学生在没有明确研究计划和指导的情况下,容易迷失在科研工作中,不知道如何推进项目,从而产生焦虑和无助感。
In each room of the hotel, a section of the original floor was retained and turned into a sunken stone garden, framed by a metal railing. The design aims to create the impression of being in an archaeological site, where visitors can take in the original dimensions of the room and its ...
A decade after mitochondrial supercomplexes were recognized as vital membrane entities, understanding their structure-function relationship remained challenging due to high heterogeneity. This study from Kai Zhang's lab and collabo...
In situ architecture of the ER–mitochondria encounter structure 内质网-线粒体结合的原位结构 (导读 阿金)内质网与线粒体是通过膜接触位点进行脂质交换实现真核细胞膜生物发生的主要核心。本研究识别出内质网-线粒体结合结构(ERMES)的分子组织过程,通过结合定量活体成像、低温相关显微镜、副图平均化和分子建模,发现ER...
近日,生物治疗国家重点实验室邵振华研究员团队在国际期刊Nature Communications(影响因子12.1)上发表了题为“Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode”的研究论文,揭示GPCR识别药物新机制。