Stratified medicine promises to tailor treatment for individual patients, however it remains a major challenge to leverage genetic risk data to aid patient stratification. Here the authors introduce an approach to stratify individuals based on the aggregated impact of their genetic risk factor profiles ...
Here we show that human primary lung adenocarcinomas are characterized by the emergence of regenerative cell types, typically seen in response to lung injury, and by striking infidelity among transcription factors specifying most alveolar and bronchial epithelial lineages. In contrast, metastases are ...
Regenerative medicine and tissue engineering aim to promote functional rebuilding of damaged tissue. Comprehensively profiling cell identity, function and interaction in healthy tissues, as well as understanding how these change upon tissue disruption, such as that caused by injury, ageing or infection, ...
The integration of biomimetic properties into photocatalysts may enable the regeneration of damaged tissues and organs, providing new avenues for regenerative medicine. In addition, the utilization of these photocatalysts in biosensing and diagnostics holds great potential for early disease detection and ...
724 Journal Impact Factor 223.679 74.449 70.670 59.102 57.618 54.301 54.000 51.848 51.273 44.019 43.704 43.351 43.070 41.037 40.443 38.887 38.296 36.216 35.386 34.648 34.106 34.024 34.024 33.407 33.250 33.162 33.069 32.274 31.864 31.583 30.641 30.628 28.755 28.467 28.295 28.245 27.778 27.604 27.516 26.922 ...
Regenerative medicine, organ bioengineering and transplantation. Br J Surg. 2020;107(7):793–800. Article CAS PubMed Google Scholar Orlando G, Soker S, Stratta RJ. Organ bioengineering and regeneration as the new Holy Grail for organ transplantation. Ann Surg. 2013;258(2):221–32. Article...
Fig. 4: Impact of clinical factors on antiviral responses post VST therapy. Odds ratios (OR) in favor of antiviral responses (complete or partial response at day+28) based on a univariate logistic regression model are shown (n = 43). CI confidence interval, RIC reduced intensity conditio...
Dr. Clive Svendsen is the founder of the Cedars-Sinai Board of Governors Regenerative MedicineInstitute (RMI) with over 30 faculty members. Dr. Svendsen’s lab focuses on using human induced pluripotent stem cells to model a wide range of neurological diseases. The other focus of his lab is ...
He obtained his degree in Nanoscale Science and Technology and his PhD in Tissue Engineering and Regenerative Medicine from the University of Leeds. He handles papers at the interface of the physical and life sciences related to biomaterials, nanoparticle/drug delivery and biochemical/chemical and ...
I’ve been on Naturethroid for about 10 years and done great and levels remained level. The last two years I’ve become sicker and sicker. I was on 162.5 forever..Now I’m on 230 and my tsh has barely got to 26. This medicine is not the same. Now my endocrinologist is trying to...