We considered that a highly cell-type-specific regulon (CTSR) might represent only one significant enriched functionality; alternatively, a generic regulon might improperly contain genes involved in several pathways. Therefore, we compared the number of CTSRs enriched to one function/pathway across ...
Harnessing the full complexity of optical fields requires the complete control of all degrees of freedom within a region of space and time—an open goal for present-day spatial light modulators, active metasurfaces and optical phased arrays. Here, we resolve this challenge with a programmable photo...
In diverse areas of physics and engineering, structural constraints on system dynamics can be understood via the system’s eigenmodes, which are fundamental spatial patterns corresponding to the natural, resonant modes of the system12. In the linear regime, such as brain activity under normal (that...
1. Solid State Research Centre, De Montfort University, Leicester, LE1 9BH, UK 2. Solid State Research Centre and Biomolecular Sciences, De Montfort University, Leicester, LE1 9BH, UK 3. CLRC Daresbury Laboratory SRS, Warrington, WA4 4AD, UK Continue...
Self-managed teams remain an area of interest in the literature and in practice. This study draws on the experiences of four academic women from four different disciplines and uses photo-elicitation to determine the nature of self-managed teams in the academic world. Data was gathered from associ...
Improved normalization of species count data in ecology by scaling with ranked subsampling (SRS): application to microbial communities. PeerJ 8, e9593 (2020). Article PubMed PubMed Central Google Scholar Schwyn, B. & Neilands, J. B. Universal chemical-assay for the detection and ...
Our findings challenge prevailing views and identify a previously underappreciated role of geometry in shaping function, as predicted by a unifying and physically principled model of brain-wide dynamics. 大脑的解剖结构必然限制了它的功能,但具体如何限制还不清楚。神经科学中的经典和主导范例是神经元动力学...
Knowledge of electrolyte transport and thermodynamic properties in Li-ion and beyond Li-ion technologies is vital for their continued development and success. Here, we present a method for fully characterising electrolyte systems. By measuring the electrolyte concentration gradient over time via operando ...
RNAs perform their function by forming specific structures, which can change across cellular conditions. Structure probing experiments combined with next generation sequencing technology have enabled transcriptome-wide analysis of RNA secondary structure
Our findings challenge prevailing views and identify a previously underappreciated role of geometry in shaping function, as predicted by a unifying and physically principled model of brain-wide dynamics. 大脑的解剖结构必然限制了它的功能,但具体如何限制还不清楚。神经科学中的经典和主导范例是神经元动力学...