Here we define myeloid cellular states in gliomas by longitudinal single-cell profiling and demonstrate their strict control by the tumor genotype: in isocitrate dehydrogenase (IDH)-mutant tumors, differentiation of infiltrating myeloid cells is blocked, resulting in an immature phenotype. In late-stage...
In July 2012, the ATLAS and CMS collaborations at the CERN Large Hadron Collider announced the observation of a Higgs boson at a mass of around 125 gigaelectronvolts. Ten years later, and with the data corresponding to the production of a 30-times larger number of Higgs bosons, we have...
The dung beetle optimizer (DBO) considers both global exploration and local exploitation, and has a fast convergence rate and satisfactory solution accuracy, which can be effectively used to solve real-world application problems[16]. Numerous studies are also performed on dragonfly-based collective ...
Analysis of prominent research indicates that NITs based IDSs offers high detection rate and low false positive rate in comparison to the conventional IDSs. The NITs enables more flexibility in IDSs because of their employability into hybrid IDSs leading to detection on the basis of anomalies as ...
of society are developed mainly tthrough the using of innovative technologies and constant updating of products. The result of active innovative activity of thhe economic subjects directed on the solution of different financial problems including the management all of increasinng innovative risks became ...
In this thesis, an attempt is made to understand the complex nature of the foreign currency markets and how the Canadian dollar has performed in the last three decades. The study has found that commodity prices, interest rate differentials, diverging inflation rates, and political events all have...
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In short, the top chamber was perfused with N2 gas (0.1 l min−1 flow rate), establishing anoxia (roughly 0.4–0.6% O2). It was separated from the underlying microbial chamber by a nanoporous membrane (0.05 µm) coated with porcine mucin (Sigma-Aldrich), dissolved in ddH2O...
(let us assume for simplicity there is no interest rate) and we would have gained £20,000. We see, then, that an increase of 10% in the value of the house translates into an increase of 50% of our initial capital. The same is, however, true if the house is devalued: a ...
FA belongs to LNT because a firefly moves towards another firefly that has larger luminance; CS is LNT because individuals either generate new solution independently (see Equation (18)) or produce new solutions and exchange information with other individuals (see Equation (20)); similar to GA, ...