A large family of DNA viruses that can infect and cause illness in humans. Kaposi's sarcoma Cancer characterized by numerous bluish-red nodules on the skin, the development of which is mainly caused by human herpes virus 8 (also known as Kaposi's sarcoma-associated herpes virus). Burkitt's...
INS018_055-inhibitory effect (green) on EMT in primary human bronchial epithelial cells (HBECs) by measuring fibronectin. Percent remaining cells (black) reflects nuclear count, which is a measurement of cell percentage without nuclear loss (n = 2 experimental replicates). PIN, percentage inh...
miyamotoi infection generally resolve within a week of the start of antibiotic therapy. B. miyamotoi infection should be considered in patients with acute febrile illness who have been exposed to Ixodes ticks in a region where Lyme disease occurs. Because clinical manifestations are nonspecific, ...
the respiratory epithelium is of particular interest for understanding the association at 3p21.31. EMT, a developmental pathway that allows terminally differentiated epithelial cells to dedifferentiate and acquire mesenchymal identity, plays a key role in the innate immune response, is a consequence...
Integrating physical activity into mental health services for persons with serious mental illness. Psychiatr. Serv. 2005, 56, 324–331. [CrossRef] [PubMed] 15. Johansson, M.; Hartig, T.; Staats, H. Psychological benefits of walking: Moderation by company and outdoor environment. Appl. ...
We conclude that pulmonary epithelial cells undergoing EMT, rather than immune cells, are likely responsible for the 3p21.31-associated risk. Since the 3p21.31 effect is conferred by a gain-of-function, LZTFL1 may represent a therapeutic target....
5,11,12). The majority of infected men (>50%) shed ZIKV RNA in semen. The shedding peaks between 8 and 30 days after onset of the illness, followed by gradual viral clearance, which in some individuals takes up to 10 months13,14,15. Infectious ZIKV has also been recovered from a ...
Down syndrome (DS), the genetic condition caused by trisomy 21, is characterized by variable cognitive impairment, immune dysregulation, dysmorphogenesis and increased prevalence of diverse co-occurring conditions. The mechanisms by which trisomy 21 causes these effects remain largely unknown. We demonstr...
A wasting or weakening of the body owing to chronic illness or cancer. Nanobody An engineered single-domain antibody. Rights and permissions Reprints and permissions About this article Cite this article Jones, S.A., Jenkins, B.J. Recent insights into targeting the IL-6 cytokine family in infl...
7. Endpoints were vaginal bleeding, severe abdominal distension, and signs of severe illness, such as dehydration, hunching, jaundice, ruffled fur, signs of infection, or non-responsiveness. Sample sizes within each genotype were chosen based on the proportions of animals with vaginal bleeding ...