Deep Learning based approaches for protein structure prediction have sent shock waves through the structural biology community. We anticipate far-reaching and long-lasting impact.
Nature Methods volume 18, pages 9–14 (2021)Cite this article 164k Accesses 401 Altmetric Metrics details A Publisher Correction to this article was published on 19 January 2021This article has been updatedNature Methods has crowned spatially resolved transcriptomics Method of the Year 2020. This ...
Method of the Year 2023: methods for modeling development KO/CKO小鼠,交付纯合子,更有精美礼品赠送! >> Arraystar Small RNA表达芯片——同时检测多种small RNA分子的表达水平 >>
11. Method of the Year: protein structure prediction 年度方法:蛋白质结构预测 蛋白质结构预测是我们的 2021 年度方法,用于最近开发的基于深度学习的方法,该方法以前所未有的准确度预测结构。在封面上,来自AlphaFold蛋白质结构数据库(https://alphafold.ebi.ac.uk/)的大量蛋白质结构模型由AlphaFold2方法预测。
At the close of 2012 at Nature Methods, we continue our annual celebration of biological research methods with our choice of targeted proteomics as Method of the Year. Our choice is a little different from those of previous years, when we highlighted very new, cutting-edge techniques such as ...
In our annual toast to biological research methods and to the scientists who develop them, we have chosen genome editing with engineered nucleases as our Method of the Year 2011. Perhaps the most reliable way to learn about the function of a gene or protein is to specifically perturb it and...
[2] 随后光遗传学曾在 2007 年被麻省理工评选为年度十大最有影响的技术之一,并且在 2010 年入选《Nature Methods》杂志的 Method of the year 和《Science》杂志的 breakthroughs of the decade。[3,4,5] 然而,在光遗传学充满鲜花和闪光灯的舞台背后,还有一位华人科学家的身影被人遗忘⸺底特律韦恩州立大学医...
Other methods exploit a CRISPR-based method called prime editing to introduce short ‘landing pad’ sequences that selectively recruit enzymes that in turn can precisely splice large DNA fragments into the genome. In 2022, for instance, genome enginee...
11. Method of the Year: protein structure prediction 年度方法:蛋白质结构预测 蛋白质结构预测是我们的 2021 年度方法,用于最近开发的基于深度学习的方法,该方法以前所未有的准确度预测结构。在封面上,来自AlphaFold蛋白质结构数据库(https://alphafold.ebi.ac.uk/)的大量蛋白质结构模型由AlphaFold2方法预测。1...
Spatial transcriptomics (ST) measures mRNA expression across thousands of spots from a tissue slice while recording the two-dimensional (2D) coordinates of each spot. We introduce probabilistic alignment of ST experiments (PASTE), a method to align and i