EVEscape was as good as or better than the latest DMS scans at anticipating pandemic variation (50% versus 46% predicted mutations observed, respectively, when considering the top decile of prediction) (Fig.3a). As we considered higher-frequency mutations, EVEscape increasingly predicted a greater...
have acquired RBD mutations on K478. However, the K478 mutation did not emerge in our prediction of evolutionary trends for XBB.1.5 RBD. This contradiction may be attributed to the fact that our mutational prediction model relies primarily on the cohorts that we recruited, and we did not capt...
Anu Eskelinen and her colleagues show that a key factor driving this reduction is competition among plant species for light. Working on German grassland, the researchers used lamps placed close to ground level to counteract the shading effect from vigorous...
Automated real-world data integration improves cancer outcome prediction A study generates a clinicogenomics dataset resource, MSK-CHORD, that combines natural language processing-derived clinical annotations with patient medical data from various sources to improve models of cancer outcome. ...
Accessed 11 Dec 2023. Wand, H. et al. Improving reporting standards for polygenic scores in risk prediction studies. Nature 591, 211–219 (2021). Article CAS PubMed PubMed Central Google Scholar Khan, A. et al. Genome-wide polygenic score to predict chronic kidney disease across ances...
Article | 13 December 2023 A unified explanation for the morphology of raised peatlands Physical analysis of processes universal to raised peatlands produces an equation that explains their morphology and carbon storage across biomes, from Alaska to New Zealand. Alexander R. Cobb , René Dommain...
Organizational type has no statistical relationship with prediction accuracy. The more-accurate predictions came from experts who were systematically more optimistic in their low- and median-cost estimates and those who expressed greater uncertainty in their predictions through a larger spread between those...
We speculate that there may be many more uncharacterized functional states of proteins present that this method could identify. The AlphaFold protein structure prediction database55contained 214 million predictions of single structures as of June 2023. If the previous estimate29that 0.5–4% of all...
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Water Balance Prediction in Stormwater Infiltration Basins Using 2-D Modeling: An Application to Evaluate the Clogging Process. Int. J. Sediment Res. 2018, 33, 371–384. [Google Scholar] [CrossRef] Alam, M.F.; Pavelic, P. Underground Transfer of Floods for Irrigation (UTFI): Exploring ...