Nature Chemical Biology is an international journal publishing research and commentary at the interface of chemistry, biology and allied disciplines.
Chemical biology articles within Nature Featured Article 29 January 2025|Open Access C-terminal amides mark proteins for degradation via SCF–FBXO31 SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation....
The field of chemical biology has changed dramatically over the past 20 years. Here, we speak to Sarah E. O’Connor, Benjamin F. Cravatt and Chengqi Yi about the major changes that have affected the field, the advances that have affected them and their research, and their thoughts about th...
The third Nature Chemical Biology symposium brought together nearly 200 scientists to explore the frontiers of chemical biology and drug discovery. In the past decade, chemical biology has expanded to embrace increasingly diverse research areas at the interface of chemistry and biology. Nature Chemical ...
News & Views14 Feb 2025Nature Chemical Biology P: 1-2 REPLACE-ing RNA through evolution Directed evolution is commonly performed in prokaryotic or yeast systems, but platforms are needed to enhance functions in mammalian cells. Now, a tool known as RNA replicase-assisted continuous evolution (REPL...
Nature Chemical Biology https://www.nature.com/nchembio/ Yiyun Song Corresponding author Correspondence to Yiyun Song. Rights and permissions Reprints and permissions About this article Cite this article Song, Y. One-way Integrator. Nat Chem Biol 20, 657 (2024). https://doi.org/10.1038/s41589...
Chemical biology tools take the strain Bioorthogonal chemistry has become a mainstay technique used by chemists and biologists alike. Here we look back at one of its key reactions: strain-promoted azide–alkyne cycloadditions (SPAAC). Owing to its robustness, simplicity and applicability to living ...
Natural products research focuses on the chemical properties, biosynthesis and biological functions of secondary metabolites. As our scientific understanding of all things 'natural' is rapidly expanding, we should also make time to communicate the subtle
Nature Chemical Biology is an international monthly journal that provides a high-visibility forum for the publication of top-tier original research and commentary for the chemical biology community. Chemical biology combines the scientific ideas and approaches of chemistry, biology and allied disciplines ...
Nature Cell Biology publishes research of the highest quality across all areas of cell biology, encouraging studies that shed light on the mechanisms underlying fundamental cell biological processes in physiology and disease.