Somatic copy number alterations (CNAs) are major mutations that contribute to the development and progression of various cancers. Despite a few computational methods proposed to detect CNAs from single-cell transcriptomic data, the technical sparsity of
Global Change Data Lab (Registered Charity Number 1186433, Charities Commission for England and Wales) is supported by grants from the Department of Health and Social Care in the United Kingdom and the Bill and Melinda Gates Foundation, as well as donations from thousands of individuals and ...
reward23. Further, altruism is itself rewarding51. However, while exogenous manipulations of warm glow enhance cooperation, the mechanisms by which they achieve this are unknown52,53. Fig. 1: Theoretical models linking warm glow to cooperation. a, Current knowledge. Summary of the general findings...
Her thoughts serve to present a youth view and a mental health perspective on the value of an urban ‘nature place’ in her northern UK city. And while not representative of all our participants, it points to a more positive, and certainly more nuanced, youth-nature relationship than many ...
Paired-end reads from sequencing were trimmed using trimgalore (v.0.4.4, https://www.bioinformatics.babraham.ac.uk/projects/trim_galore/), removing low-quality (Q30) bases and adaptor sequences and clipping ten bases from each end of the read pairs. Trimmed reads were then mapped to hg19...
These donations are distributed among nine local charities, carefully chosen for their impactful work in the community. This initiative not only minimizes waste but also supports those in need, aligning seamlessly with our commitment to nurture both people and the planet. These initiatives not only...
Schools, community groups and charities supporting those who might struggle to visit nature can apply from now until 31 December 2024. The successful groups will be exploring nature throughout 2025, and I’m looking forward to hearing more of their stories. "Just spending one day in nature can...
creative power share skills, work on providing solutions and making things happen for conservation and outdoors charities. With people like this on the team, the weight of the larger conservation and ‘nature’ charities have a real chance of creating change....
A survey of 1,200 children in the UK by the Royal Society for the Protection of Birds (RSPB, 2013) concluded that children in urban areas were more highly connected to nature than children in rural areas, while Luck et al. (2011) found little evidence of a relationship between nature ...
683 UK Biobank participants to construct a heart shape atlas from bi-ventricular end-diastolic surface mesh models through principal component (PC) analysis. Genome-wide association studies were performed on the first 11 PCs that captured 83.6% of shape variance. We identified 43 significant loci, ...