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N), the EOM comb modulation frequencyfmand the programmable waveshaper are adjusted to precisely match the frequencies of LO pairs toωp ± N × D1, whereNis the relative mode number
Recombinant adeno-associated viruses (rAAVs) have emerged as promising gene therapy vectors due to their proven efficacy and safety in clinical applications. In non-human primates (NHPs), rAAVs are administered via suprachoroidal injection at a higher do
Esteras, N. & Abramov, A. Y. Nrf2 as a regulator of mitochondrial function: energy metabolism and beyond.Free Radic. Biol. Med.189, 136–153 (2022). ArticleCASPubMedGoogle Scholar Gureev, A. P., Shaforostova, E. A. & Popov, V. N. Regulation of mitochondrial biogenesis as a way...
Nonetheless, Σ[x]n,2d provides a high-quality approximation of Pn,2d, since each non-negative polynomial can be approximated (in the ℓ1 norm of its coefficient vector) to any desired accuracy ϵ > 0 by a sequence of sum-of-squares65. If the maximum degree d is unknown, we ...
High-velocity stars and peculiar G objects orbit the central supermassive black hole (SMBH) Sagittarius A* (Sgr A*). Together, the G objects and high-velocity stars constitute the S cluster. In contrast with theoretical predictions, no binary system near Sgr A* has been identified. Here, we...
The gastrointestinal tract maintains energy and glucose homeostasis, in part through nutrient-sensing and subsequent signaling to the brain and other tissues. In this review, we highlight the role of small intestinal nutrient-sensing in metabolic homeost
First, 2 g polyvinyl alcohol (PVA, MW ≈ 145000, Aladdin Industrial Corporation) is dissolved into 18 g deionized (DI) water by magnetic stirring at 90 °C for 2 hours. After cooling the solution to room temperature, 1.65 mL phosphoric acid (H3PO4, GR, ≥ 85% ...
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Using this model and chemogenomic analyses, we define the function of three uncharacterized essential genes with roles in kinetochore function, mitochondrial integrity, and translation, and identify the glutaminyl-tRNA synthetase Gln4 as the target of N-pyrimidinyl-β-thiophenylacrylamide (NP-BTA), ...