Elongin is a heterotrimeric elongation factor for RNA polymerase (Pol) II transcription that is conserved among metazoa. Here, we report three cryo-EM structures of human Elongin bound to transcribing Pol II. The structures show that Elongin subunit ELOA
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Urban areas are the largest source of pollutants that directly or indirectly will end up in the air, soil, and water. It is paramount to find solutions to reduce the impact of pollution on climate change, ecosystem services, biodiversity loss, and human
The Coronavirus Disease 2019 (COVID-19) pandemic has threatened global mental health, both indirectly via disruptive societal changes and directly via neuropsychiatric sequelae after SARS-CoV-2 infection. Despite a small increase in self-reported mental health problems, this has (so far) not translat...
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