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chronic problems resulting from cumulative organ injury can lead to severe morbidity191(Figs 5,6). Chronic pain is common; the Pain in Sickle Cell Epidemiology Study (PiSCES) found that adults with SCD have pain on 55% of days192, and pain, in general, is a poorly ...
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(GNATs) using acetyl-CoA as a donor molecule for lysine acetylation5,6,7,8. These enzymes structurally resemble mammalian GNATs in their active site architecture5,7,9,10,11,12. Bacterial GNATs are classified into several different subgroups depending on the presence of additional C- and/or N...
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(dash black line) shows a clean bandgap of the bulk ZnSe. In case of the (100) ZnSe surface where atoms are under-coordinated, trap states are introduced into the bandgap with the present of dangling bonds (solid black line). The pDOS (colored solid lines) is used to analyze which ...
The degeneration of forebrain dopamine systems in Parkinson's disease has been an effective target for pharmaceutical research over the past four decades. However, although dopamine replacement may alleviate the symptoms of the disease, it does not halt