Nature volume 611, pages 271–277 (2022)Cite this article 44k Accesses 233 Citations 76 Altmetric Metrics details Abstract Conducting polymers (CPs) with high conductivity and solution processability have made great advances since the pioneering work on doped polyacetylene1,2,3, thus creating the ...
Nature 611, 271–277 (2022). Article CAS PubMed Google Scholar Heywang, G. & Jonas, F. Poly(alkylenedioxythiophene)s—new, very stable conducting polymers. Adv. Mater. 4, 116–118 (1992). Article CAS Google Scholar Russ, B., Glaudell, A., Urban, J. J., Chabinyc, M. L. &...
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Ageing impairs a wide range of cellular processes, many of which affect the quality and concentration of proteins. Among these, transcription is particularly important, because it is a main regulator of protein levels7,8,9. Transcriptional elongation is critical for proper mRNA synthesis, owing to ...
Asp611 and His613 (Fig.3b). Metal ion coordination stabilizes the flexible capping loop 590–610 into a conformation that completely plugs the LH catalytic site, in proximity to the dimer interface (Supplementary Fig.16A). We could observe a very similar arrangement, although slightly more flexib...
2022年中美两国的研究人员共同在《Nature Reviews Nephrology》杂志发表了一篇名为“Cellular senescence: the good, the bad and the unknown”的综述。作者总结了细胞衰老的机制、特征和结果,以及衰老靶向干预的治疗潜力。 20世纪60年代,人类二...
再生医学在治疗以细胞丢失为特征的疾病方面具有广阔的应用前景。皮肤细胞或星形胶质细胞等细胞类型可通过强制性表达转录因子、microRNA或小分子等方法在体外将其转化为其他细胞类型(1)。 通过干细胞重编程技术将小鼠大脑中星形胶质细胞变成具有...
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Chemical strategies to using small molecules to stimulate hypoxia inducible factors (HIFs) activity and trigger a hypoxic response under normoxic conditions, such as iron chelators and inhibitors of prolyl hydroxylase domain (PHD) enzymes, have broad-spe
The Earth system is maintained in a unique state far from thermodynamic equilibrium, as, for instance, reflected in the high concentration of reactive oxyg