Nature volume 605, pages 262–267 (2022)Cite this article 30k Accesses 185 Citations 96 Altmetric Metrics details Abstract The scaling of silicon metal–oxide–semiconductor field-effect transistors has followed Moore’s law for decades, but the physical thinning of silicon at sub-ten-nanometre ...
a, The volume of Lifeact–GFP-labelled MDA-MB-231 cells (n ≥ 28) at the indicated viscosities from 3 experiments.b, Confocal images of confined MDA-MB-231 cells stained for NHE1 and phalloidin.c, Front-to-rear NHE1 intensity ratio in NHE1-immunostained cells (n ≥ 16) fro...
a,b, SEM imaging of fixed ‘Ca.L. ossiferum’ cells showed small coccoid cells with extensive protrusions. Example micrographs fromn = 2 independent cultures are shown. See also Extended Data Fig.7d. Foraandb, scale bars, 500 nm.c–f, Slices through cryo-tomograms (c,e; thickne...
This work was supported by the National Natural Science Foundation of China (Grant Nos. 42272053 and 41930215), the MOST Special Fund from the State Key Laboratory of Geological Processes and Mineral Resources (Grant No. MSFGPMR2022-6).
(Supplementary Fig.1b). As a control, MBP fusion of a 220 amino acid UBA1 N-terminal fragment did bind to UBE2G2 and AF also had no effect (Supplementary Fig.1b). It is worth noting that 6His-UBA1 and MBP-UFD were preincubated with AF and unbound AF was removed before being ...
displayed everything a participant needed to complete the full elicitation process, consisting of a consent form, background information on the elicitation process, the Earth system processes, the control variables to be assessed, a question example and a dashboard for selecting specific interactions...
A growing body of work suggests that the material properties of biomolecular condensates ensuing from liquid–liquid phase separation change with time. How this aging process is controlled and whether the condensates with distinct material properties can
Analyzing proteins from single cells by tandem mass spectrometry (MS) has recently become technically feasible. While such analysis has the potential to accurately quantify thousands of proteins across thousands of single cells, the accuracy and reproduc
further acceleration of lysine conjugate formation, and inhibition of tubular albumin uptake. Lysine also conjugates with malonyl-CoA to form a novel metabolite Nε-malonyl-lysine to deplete malonyl-CoA from fatty acid synthesis. Through conjugate formation and excretion as fructoselysine, saccharopine,...
whereφ0is the Josephson phase of a dc current across the junction,EC,m(φ0) is the capacitive energy of the qubit mode,EL,m(φ0) is the inductive energy of the qubit mode,ELis the inductive energy of the dc current,EJis the Josephson energy, and\({\hat{n}}_{m}\)and\({\hat{...