Elongin is a heterotrimeric elongation factor for RNA polymerase (Pol) II transcription that is conserved among metazoa. Here, we report three cryo-EM structures of human Elongin bound to transcribing Pol II. The structures show that Elongin subunit ELOA
Urban areas are the largest source of pollutants that directly or indirectly will end up in the air, soil, and water. It is paramount to find solutions to reduce the impact of pollution on climate change, ecosystem services, biodiversity loss, and human
Shortly after the emergence of a novel coronavirus towards the end of 2019, the virus was named SARS-CoV-2 by the WHO, and the corresponding disease was termed coronavirus disease (COVID-19)1. COVID-19 has a mild or moderate course in most people without comorbidities, whereas patients wit...
Shortly after the emergence of a novel coronavirus towards the end of 2019, the virus was named SARS-CoV-2 by the WHO, and the corresponding disease was termed coronavirus disease (COVID-19)1. COVID-19 has a mild or moderate course in most people without comorbidities, whereas patients wit...
7, 4698–4707 (2019). Article CAS Google Scholar Tang, Y. et al. SiRNA crosslinked nanoparticles for the treatment of inflammation-induced liver injury. Adv. Sci. 4, 1600228 (2017). Article CAS Google Scholar Dash, B. C. et al. An injectable elastin-based gene delivery platform for ...
223–269 (Overseas Publishers Association, 2001). Mühlbauer, S. et al. Magnetic small-angle neutron scattering. Rev. Mod. Phys. 91, 015004 (2019). ADS MathSciNet Google Scholar Radlinski, A. P. & Hinde, A. L. Small angle neutron scattering and petroleum geology. Neutron. N. 13, ...
48kAccesses 217Citations 478Altmetric Metrics Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has threatened global mental health, both indirectly via disruptive societal changes and directly via neuropsychiatric sequelae after SARS-CoV-2 infection. Despite a small increase in self-reported ment...