Dash, P. et al. Quantifiable predictive features define epitope-specific T cell receptor repertoires. Nature 547, 89–93 (2017). Article CAS PubMed Central PubMed Google Scholar Chronister, W. D. et al. TCRMatch: predicting T-cell receptor specificity based on sequence similarity to previou...
Paclitaxel is an anticancer therapeutic produced by the yew tree. Over the last two decades, a significant bottleneck in the reconstitution of early paclitaxel biosynthesis has been the propensity of heterologously expressed pathway cytochromes P450, inc
Dash, P. et al. Quantifiable predictive features define epitope-specific T cell receptor repertoires. Nature 547, 89–93 (2017). Article CAS PubMed Central PubMed Google Scholar Chronister, W. D. et al. TCRMatch: predicting T-cell receptor specificity based on sequence similarity to previou...
Metformin increases levels of growth differentiation factor 15 (GDF15) in the kidney and circulation to activate glial cell line-derived neurotrophic factor family receptor ɑ-like (GFRAL) in the area postrema to reduce body weight. This is a preview of subscription content, PubMed CentralGoogle ...
Dash, P. et al. Quantifiable predictive features define epitope-specific T cell receptor repertoires. Nature 547, 89–93 (2017). Article ADS CAS PubMed PubMed Central Google Scholar Bassez, A. et al. A single-cell map of intratumoral changes during anti-PD1 treatment of patients with brea...
AMP-forming acetyl-CoA synthetases contain a large N-terminal domain of app. 450-500 amino acids composed of two mostly parallel eight-stranded β-sheets, i.e. β-sheet A and β-sheet B, surrounded by several α-helices providing binding sites for CoA and ATP, and an additional β-sheet...
Urban areas are the largest source of pollutants that directly or indirectly will end up in the air, soil, and water. It is paramount to find solutions to reduce the impact of pollution on climate change, ecosystem services, biodiversity loss, and human
Excitation spectra were recorded using emission at 550 nm, excitation from 380 to 535 nm in steps of 2 nm. Kinetics of l-2-HG binding by LHGFR were assessed by using SX-20 stopped-flow fluorimeter (Applied Photophysics, UK). Equal volumes of 1 μM purified LHGFR in 50 mM...
reflected that the interaction intensity between acid groups and water molecules followed the order of –SO3H > –PO3H2> –CO2H. The dash blue line attributed to the first derivative of RDF for O atoms was used to describe the number of adsorbed water molecules, which followed the trend of...
AMP-forming acetyl-CoA synthetases contain a large N-terminal domain of app. 450-500 amino acids composed of two mostly parallel eight-stranded β-sheets, i.e. β-sheet A and β-sheet B, surrounded by several α-helices providing binding sites for CoA and ATP, and an additional β-sheet...