Recombinant adeno-associated viruses (rAAVs) have emerged as promising gene therapy vectors due to their proven efficacy and safety in clinical applications. In non-human primates (NHPs), rAAVs are administered via suprachoroidal injection at a higher do
To identify reference samples with extensive admixture to exclude from LAI, we performed admixture analysis with the program TeraSTRUCTURE (https://github.com/StoreyLab/terastructure) on a merged genotyping dataset (n = 3,274) that included African (AFR), European (EUR) and American (AMR)...
Bolourchian, N. & Dadashzadeh, S. pH-independent release of propranolol hydrochloride from HPMC-based matrices using organic acids. Daru 16, 136–142 (2008). CAS Google Scholar Dvorˇácˇková, K. et al. The effect of acid pH modifiers on the release characteristics of weakly basic drug...
165, 78–87 (2022). Google Scholar Gherman, I. M. et al. Bridging the gap between mechanistic biological models and machine learning surrogates. PLoS Comput. Biol. 19, e1010988 (2023). Article Google Scholar Sapoval, N. et al. Current progress and open challenges for applying deep ...
The estimated hydrogen bonds are represented with red dash lines. i, Representative curve for effects of the S802.61A, R832.64A and H993.28A mutations in hTAAR1 on ligands (fenoldopam, A77636, T1AM, SEP-363856) induced Gs signalling using CAMYEL assay. Data are presented as mean ±...
The Special Nature Reserve, a part of the nature “Meadows of Great Bustard” (MGB), is a protected area with an extremely rare and sensitive ecosystem. The MGB spreads in the northeast of Vojvodina in Serbia. The natural potentials of MGB, in addition t
81, 1301–1350 (2009). ADS Google Scholar Shor, P. & Preskill, J. Simple proof of security of the BB84 quantum key distribution protocol. Phys. Rev. Lett. 85, 441 (2000). ADS CAS PubMed Google Scholar Gottesman, D., Lo, H.-K., Lütkenhaus, N. & Preskill, J. Security of...
(ECS), the eastern part of the warm pool and eastern Indian Ocean (EIO), the equatorial Pacific (Eq) and South Pacific (Supplementary Fig.9). Yellow and blue bars indicate the early Holocene (EH) and last glacial (LG), respectively. The vertical dash lines denote the precession maximum ...
Bolourchian, N. & Dadashzadeh, S. pH-independent release of propranolol hydrochloride from HPMC-based matrices using organic acids. Daru 16, 136–142 (2008). CAS Google Scholar Dvorˇácˇková, K. et al. The effect of acid pH modifiers on the release characteristics of weakly basic drug...
the dash-dotted black line is the predicted astrometric detection limit of Gaia DR4 release (expected not before the end of 2025) for G-dwarfs at 50 pc81,82, comparable to the median distance of the BPMG members. The light blue area is the one corresponding to the Jupiter-like planets....