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Intestinal organoids derived from single cells undergo complex crypt–villus patterning and morphogenesis. However, the nature and coordination of the underlying forces remains poorly characterized. Here, using light-sheet microscopy and large-scale imag
The most recognizable feature of graphene’s electronic spectrum is its Dirac point, around which interesting phenomena tend to cluster. At low temperatures, the intrinsic behaviour in this regime is often obscured by charge inhomogeneity1,2 but thermal
The immune system is intimately involved in the pathophysiology of heart failure. However, it is currently underused as a therapeutic target in the clinical setting. Moreover, the development of novel immunomodulatory therapies and their investigation for the treatment of patients with heart failure are...
Five hundred sequences were selected from available closely related sequences in a time stratified manner, taking every N/500th sequence from the set of N sequences arranged by date, rounded to the nearest integer. For each Nextstrain clade a maximum-likelihood phylogeny was produced with IQTree...
in the derivation cohort (n = 72, not exposed to training) and the independent validation cohort (n = 63). In each comparison the F2, I2 or S1 proteomics model serves as the new model while the clinical test in comparison serves as the baseline model. The formula is as ...
In the breeding areas of residents from higher latitudes (N=50), short-distance (N=230) and long-distance migrants (N=87), there is a larger decrease in EVI during winter (PGLS, P value<0.001, Supplementary Table 10) compared with residents from mid (N=326) and low (N=459) ...
Sreelaja N, Pai GV (2014) Swarm intelligence based approach for sinkhole attack detection in wireless sensor networks. Appl Soft Comput 19:68–79 Google Scholar Srinoy S (2007) Intrusion detection model based on particle swarm optimization and support vector machine. In: IEEE symposium on comp...
N., Clifton, G. L. & Dash, P. K. Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury. J. Neurosci. Res. 82, 499–506 (2005). Article CAS PubMed Google Scholar Benedict, A. L. et al. Neuroprotective effects of sulforaphane after ...
Collagen proteins contain a characteristic structural motif called a triple helix. During the self-assembly of this motif, three polypeptides form a folding nucleus at the C-termini and then propagate towards the N-termini like a zip-chain. While polypep