Nature封面:像真正“折纸”的DNA折纸 2006年,美国科学家Paul Rothemund发明了一项名为“DNA折纸(DNA origami)”的技术,用一条具有7000个碱基对的DNA链段,通过弯曲、折叠出一个笑脸[1]。这项工作被誉为DNA纳米技术领域的一项里程碑,极大促进了纳米尺度DNA结构的精确构建。近年来,科学家借鉴该技术,从1维到3...
2006年,加州理工学院的Paul Rothemund教授开发了一种将DNA长链折叠成特定形状的方法。这种被称为DNA折纸的技术使得科学家能够创造出自组装DNA结构,从而实现任何特定的图案,比如100纳米宽的笑脸(Nature 440, 297-302)。DNA折纸术为纳米科技领域带来了革命性的改变,打开了构建微型分子器件和“智能”可编程材料的大门。
Nature 440, 297–302 (2006). Article ADS CAS PubMed Google Scholar Cui, J. et al. Nanomagnetic encoding of shape-morphing micromachines. Nature 575, 164–168 (2019). Article ADS CAS PubMed Google Scholar Hawkes, E. et al. Programmable matter by folding. Proc. Natl Acad. Sci. USA ...
Nature 440, 297–302 (2006). Article CAS Google Scholar Shih, W. M., Quispe, J. D. & Joyce, G. F. A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature 427, 618–621 (2004). Article CAS Google Scholar Wei, B., Dai, M. J. & Yin, P. ...
Nature 440, 297–302 (2006) Article CAS ADS Google Scholar Douglas, S. M. et al. Self-assembly of DNA into nanoscale three-dimensional shapes. Nature 459, 414–418 (2009) Article CAS ADS Google Scholar Hong, F., Zhang, F., Liu, Y. & Yan, H. DNA origami: scaffolds for ...
440 eLife 441 Journal of Allergy and Clinical Immunology-In Practice 442 JOURNAL OF AUTOIMMUNITY 443 Environmental Innovation and Societal Transitions 443 Environmental Innovation and Societal Transitions 445 CURRENT OPINION IN PLANT BIOLOGY 446 IEEE NETWORK IEEE TRANSACTIONS ON INDUSTRIAL 446 ELECTRONICS 448...
Senescent cells accumulate throughout the body with advanced age, diseases and chronic conditions. They negatively impact health and function of multiple systems, including the central nervous system (CNS). Therapies that target senescent cells, broadly
图片选自《折叠DNA以形成纳米尺度的形状和图案》一文(440, 297-302; 2006)。文中美国加州理工学院的科学家保罗·罗特蒙德利用纳米技术,能够设计DNA使其折叠成几乎任意的二维图案。 5 文献须多读 爱因斯坦曾说过:“我们的科学进步得如此之...
原文:Nature 440, 297-302 (16 March 2006) | doi:10.1038/nature04586 Folding DNA to create nanoscale shapes and patterns Paul W. K. Rothemund (生物通:万纹) 附:据路透社16日报道,美国一位科学家将手工折纸艺术发展到了一个新高度:用DNA分子、而非纸作为材料。
8 Rothemund, P. W. Folding DNA to create nanoscale shapes and patterns.Nature440, 297-302, doi:10.1038/nature04586 (2006). 9 Douglas, S. M. et al. Self-assembly of DNA into nanoscale three-dimensional shapes.Nature459, 414-418, doi:10.1038/nature08016 (2009). ...