The overall increase is observed significantly among those above 60 years old, hinting towards a potential role of the aging process in the development and progression of the disease due to the nature in which the cellular damage accumulates, eventually leading to symptoms later in life. Conventiona...
Natural products (NPs) have various sources in nature and have served as a cornerstone in the search for new cancer therapies because of their diverse biological activities and chemical structures [14] (Fig.1). Although a series of studies have helped elucidate the anticancer mechanisms of NPs, ...
The present review focus on the possible applications of natural products from various biological sources in skin care cosmetics, including topical care products, fragrances, moisturizers, UV protective, and anti-wrinkle products. In addition, the mechanisms of targets for evaluation of active ...
can lead to reduced respiratory function and, in severe cases, respiratory failure. The side effects of current treatments, such as hormone therapy, drugs, and radiotherapy, highlight the need for new therapeutic strategies. Traditional Chinese Medicine (TCM) offers a promising alternative, leveraging...
Tumor cells produce much more ROS than normal cells which damage killing effect of NK cells. For instance, chronic myelogenous leukemia (CML) cells can motivate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase to generate and then paracrine ROS, contributing to the dysfunction of NK cells...
It is recognized to possess substantial amounts of vitamin A, similar to that relating to carrots. In combination with the A, B and C vitamins, it furthermore support calcium, iron, plus phosphorus. Product name Acerola Cherry Extract Plant sources Malpighia glabra L. Apperance P...
and that by inhibiting CK1 activity or lowering the level of CK1, autophagic activity and promoting apoptosis in multiple myeloma cells can be reduced, thereby inhibiting tumor growth and survival (Carrino et al.2019).Yumeng Zhang et al. demonstrated that nicotinamide promoted the differentiation of...
Natural products and their derivatives are important sources of effective drug candidates. Indeed, many natural products have been approved for treating diseases, including cancer, auto- immune, and infectious diseases [38]. We have gained experience in identifying natural product-based drug candidates ...
Natural compounds are bioactive substances derived from natural sources that have therapeutic potential due to their antioxidant, anti-inflammatory, or antifibrotic properties [9]. Many studies have been conducted on the potential of natural compounds to alleviate DN by targeting the TLR4 signaling pathwa...
of NK cell therapies include the use of allogenic cell sources, off-the-shelf availability, and no risk of graft-versus-host disease (GvHD). Allogeneic NK cell therapies have reached the clinical stage as ex vivo expanded and differentiated non-engineered cells, as chimeric antigen receptor (...