Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. Eur J Pharmacol. 2002 Oct 11;452(3):295-301. Szaflarski JP et al; CBD EAP study group. Long-term safety and treatment effects of cannabidiol in children and adults with treatment-...
In the majority seizures are easily controlled with medication, and at least 50% of those who remain seizure-free at 2 years are later able to withdraw medication without recurrence. Those in whom seizures fail to respond to the first antiepileptic drug are more likely to develop refractory ...
Resveratrol (RES) is a natural plant antitoxin for the treatment of neurological disorders associated with mitochondrial dysfunction, with neuroprotective, antioxidant, and anti-inflammatory properties [100,101]. Moreover, RES increases mitochondrial biogenesis and improves mitochondrial number by activating ...
The prevalence of febrile seizure was also investigated. No significant difference was observed between groups (IQSEC2 males: 0%, IQSEC2 females: 25% and RTT: 20%, p = 0.380). Information was unavailable for 4 patients (n = 2 males, n = 2 females). Examined GID symptoms included constip...
Narcolepsy is a chronic condition for which there is no cure." Research has shown that narcolepsy is not a type of seizure, fainting episode, or psychological illness. Symptoms of narcolepsy include: Excessive daytime sleepiness: Affected individuals have an uncontrollable need to sleep during the ...
Sadly, the proportion of those not becoming seizure-free despite treatment does not seem to have improved substantially over the past 50 years. There is emerging evidence that natural history of epilepsies is more complex than previously thought. Although two-thirds of patients ...
In adults, PON1 is predominantly produced by the kidney and the bone. PON1 circulates in the blood at a concentration range of 100-300 pg/m.In normal adults, hepatocytes have a quiescent, highly differentiated phenotype and rarely divide in human or animal livers. However, their innate ...
I experienced the agony for the first time when I could not calm down my crying first born. I thought the baby had gas, maybe colic. The conventional treatment at the time was phenobarbital, an anti-seizure sedative medication. For Infants For Children For Adults For Mature Adults and those...
Also, we performed full necropsy of all the cases and did not find lesions that would cause seizures, thus AT8-positivity and the severe neuronal loss are not related to seizure activity in cats. Authors' contributions JKC, TTokuda and KU designed the study. JKC, TTokuda, KU, RI and HT...
for the treatment or prevention of COVID—for example, the number of studies looking into vitamin D supplements’ benefits with COVID is skyrocketing. If it turns out the evidence of benefit is strong, we will see a second explosion in interest sur...