During the last two decades, the commercialization of other synthetic phosphodiesterase 5 (PDE5) inhibitors has been paralleled by the rise of remedies based on natural molecules from different chemical classes (flavonoids, polyphenols and alkaloids in general). In this work, a set of in silico ...
The erectile dysfunction supplements that we have reviewed here work asnatural PDE5 inhibitors, the same as what prescription drugs do. They work in blood vessels by relaxing them to allow a significant amount of blood into the penile tissues, causing an erection. These pills do the trick, and...
PDE5erectile dysfunctionflavonoidssildenafildockingIn 1998, sildenafil was marketed as the first FDA-approved oral drug for the treatment of erectile dysfunction (ED). During the last two decades, the commercialization of other synthetic phosphodiesterase 5 (PDE5) inhibitors has been paralleled by the ...
Xanthohumol was reported as one of the MMP-9 and MMP-2 inhibitors. In addition, MMP-9 may represent a valuable anti-angiogenic agent in the treatment of chronic diseases such as cancer and inflammation [41]. The mitogen-activated protein kinase (MAPK) pathway controls the growth and survival...