1999. Natural killer cells in healthy aging. Exp Gerontol 34:435-443. https://doi.org/10.1016/S0531-5565(99)00008-X.Solana, R., Alonso, M. C. & Pena, J. (1999) Natural killer cells in healthy aging. Exp. Gerontol. 34: 435- 443....
Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we review recent insights into the role of NK cells in viral infections, with particular emphasis on human studies. We first discuss NK cells in the context of acute viral infections, with ...
Most studies on natural killer (NK) cells and aging have focused on overall cell numbers and global cytotoxic activity. NK cell functions are controlled by surface receptors belonging to three major families: killer cell immunoglobulin-like receptors (KIRs), natural cytotoxicity receptors (NCRs), and...
How does aging result in decreased effectiveness of NK cells (Natural killer cells)?Question:How does aging result in decreased effectiveness of NK cells (Natural killer cells)?LymphocytesThe lymphocytes fall under the category of white blood cells and the constituent immune cells ...
2022年3月,SENS研究基金会在Cells上发表了一篇题为“Aging of the Immune System: Focus on Natural Killer Cells Phenotype and Functions”的综述,揭示了改善NK细胞衰老在治疗与衰老相关疾病和延缓生物衰老过程中的重要作用。研究显示,衰老会导致NK细胞的数量、表型和功能的一系列变化,随着衰老发生,CD56bright NK细胞...
One of the mechanisms driving aging and neurodegenerative diseases is the accumulation of senescent cells, while their elimination mitigates age-related decline. A new report details how, with aging, changes in the dentate gyrus microenvironment lead to natural-killer-cell-mediated clearance of ...
Meanwhile, several single-cell sequencing analyses provided an in-depth knowledge of the immune landscape and immune cell infiltration patterns of ccRCC, which contributed to setting a foundation for the theoretical basis of targeted therapy [26,27,28]. Recently, natural killer (NK) cells have ...
Natural killer (NK) cells are essential components of the innate lymphoid cell family that work as both cytotoxic effectors and immune regulators. Accumulating evidence points to interactions between NK cells and the central nervous system (CNS). Here, we review the basic knowledge of NK cell biol...
M. Production of interferon-γ by natural killer cells and aging in chronic human schistosomiasis. Mediators Inflamm. 2004; 13 :327–333... E Speziali,J Bethony,O Martinsfilho,... - 《Mediators of Inflammation》 被引量: 28发表: 2004年 Production of interferon-ÃÂ by natural killer cell...
Natural Killer (NK) cells are innate immune cells that play a pivotal role as first line defenders in the anti-tumor response. To prevent tumor development, NK cells are searching for abnormal cells within the body and appear to be key players in immunos