natural killer cells are present in human lymph nodes and are activated by T cell–derived IL-2: a potential new link between adaptive and innate immunity Author links open overlay panelTodd A. Fehniger, Megan A. Cooper, Gerard J. Nuovo, Marina Cella, Fabio Facchetti, Marco Colonna, ...
Natural killer cells are activated and play a protective role against ZIKA virus infection in miceXuefeng DuanShihua LiGary WongDongfang WangHaoyu WangJiao LuYuhai BiXuancheng LuYi ShiJinghua Yan
HIV is difficult to eradicate due to the persistence of a long-lived reservoir of latently infected cells. Previous studies have shown that natural killer cells are important to inhibiting HIV infection, but it is unclear whether the administration of na
CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and ... TA Fehniger,MA Cooper,GJ Nuovo,... - 《Blood》 被引量: 1393发表: 2003年 Human natural killer cells: a unique innate immunoregulatory...
A. et al. CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity. Blood 101, 3052–3057 (2003). Article CAS PubMed Google Scholar Manser, A. R., Weinhold, S. & Uhrberg, ...
Chimeric antigen receptor-natural killer cells: a promising sword against insidious tumor cells Introduction Globally, cancer is a great threat to human health and one of the leading causes of death [1]. For decades, surgery, chemotherapy, and radiotherapy have been the main methods of treating ...
cells. This recognition represses the stimulation of NK cells and prevents them attacking the body [13,89,90,91,92]. Under stress, target cells diminish MHC-I expression. Consequently, NK cells lose repressive signaling and are activated through the “missing-self recognition” process [13,89,...
Natural killer (NK) cells are essential components of the innate lymphoid cell family that work as both cytotoxic effectors and immune regulators. Accumulating evidence points to interactions between NK cells and the central nervous system (CNS). Here, we review the basic knowledge of NK cell biol...
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse range of pathogens. Recognition of infection by NK cells is accomplished by the activation of receptors on the NK cell surface, which initiate NK cell effector functions. Many of the receptors and...
Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK cells is their ability to recognize a wide range of cells in distress, particularly tumour cells and cells infected with viruses. They combine both direct effector functions against their cellular targets ...