Natural killer (NK) cells are effector lymphocytes of the innate immune system that control several types of tumors and microbial infections by limiting their spread and subsequent tissue damage. Recent research highlights the fact that NK cells are also
Natural killer (NK) cell function (cytotoxic activity and cytokine secretion) is regulated by a balance of signals transmitted by opposing activating and inhibitory receptors. Activating NK cell receptors use transmembrane adaptor proteins such as FcɛRIγ, CD3ζ and DAP12 to stimulate the ZAP70 ...
Learn about the definition and function of natural killer cells. Understand how natural killer cells work and how they develop to fight cancer and...
Villanueva J, Filipovich A, Lee S, Passo MH, Grom AA: Natural killer cell function and perforin expression in patients with systemic onset juvenile rheumatoid arthritis as compared to macrophage activation syndrome and hemophagocytic lymphohistiocytosis [abstract]. Pediatr Blood Cancer. 2004, 43: 200...
Natural Killer Cell Function Is Well Preserved in Asymptomatic Human Immunodeficiency Virus Type 2 (HIV-2) Infection but Similar to That of HIV-1 Infection... (2006) Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar ...
To examine the cytotoxic activity of natural killer (NK) cells from peripheral blood (PB) and synovial fluid (SF) of patients with psoriatic arthritis (PsA). The influence of selected inflammatory mediators on the cytolytic function and integrin expression of NK cells was also studied.Paired sampl...
Natural killer cells: endothelial interactions, migration, and target cell recognition.cytokinestransmigrationchemokinesadhesioncytotoxicityNatural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target recognition, and function. By producing ...
Natural killer (NK) cells represent a highly specialized lymphoid population characterized by a potent cytolytic activity against tumor or virally infected cells. Their function is finely regulated by a series of inhibitory or activating receptors. The inhibitory receptors, specific for major ...
1993. Low natural killer cell function in disseminated aspergillosis . Scand. J. Infect. Dis. 25 :537–541Krishnaraj, R, Svanborg, A.Low natural killer cell function in disseminated aspergillosis. Scand. J. Infect. Dis. 1993. 25 :537-541. View this article via:...
Tumor-cell lysis by natural killer cells is regulated by inhibitory receptors for specific HLA class I alleles. Here, we report the post-grafting emergence of a large, donortype CD3+/CD8+ T cell receptor (TcR)-AB +cell population, barely detectable in normal subjects, that expresses NK recep...